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Specifications
| Appearance: | Colorless to light yellow liquid |
| Purity: | 98% min |
| Solubility: | Soluble in methanol |
| Water: | 1.0% max |
Transport Information
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Parameter |
Specification |
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UN Number |
1986 |
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Class |
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Packing Group |
II |
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H.S. Code |
2905290000301 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Keep container tightly closed in a dry and well ventilated place. Keep away from heat and sources of ignition. |
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Condition to Avoid |
Heating. |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
2MT/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2015 |
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Stock |
Applications
1. Pharmaceutical Intermediate
Used in the synthesis of pharmaceutical agents where alkyne and alcohol functionalities are important.
Acts as a key building block in the preparation of heterocycles, alkynylated drug derivatives, or API precursors.
2. Organic Synthesis
Serves as a versatile intermediate for:
Click chemistry (e.g., azide-alkyne cycloaddition to form triazoles)
Sonogashira couplings
Nucleophilic substitutions after conversion to derivatives
3. Polymer & Material Science
Can be used to introduce alkyne functional groups into polymer chains or resins.
Functionalized polymers incorporating 3-butyn-1-ol show improved properties like UV resistance or crosslinking ability.
4. Agrochemical Research
Utilized in the synthesis of plant growth regulators, pesticides, or bioactive small molecules in agrochemical R&D.
5. Flavor & Fragrance Chemistry
Employed in synthesizing complex aroma compounds or as a synthetic intermediate in perfume manufacturing.
Benefits
✅ Dual Functionality
Contains both an alkyne group (for coupling, cycloadditions) and a hydroxyl group (for esterification, oxidation, etc.), enabling flexible modification in chemical synthesis.
✅ Reactivity
The terminal alkyne is reactive and can participate in numerous reactions like:
Copper-catalyzed azide-alkyne cycloaddition (CuAAC)
Metal-catalyzed cross-coupling reactions
The hydroxyl group allows for further derivatization (e.g., to form ethers, esters).
✅ Compact Structure
Small molecular size makes it ideal for use as a starting point in stepwise organic synthesis.
✅ Widely Available and Cost-Effective
Readily accessible on an industrial scale, making it suitable for both research and production.
Conclusion
3-Butyn-1-ol (CAS 927-74-2) is a highly versatile intermediate in organic synthesis, pharmaceuticals, polymers, and fine chemicals. With its unique alkyne and alcohol dual reactivity, it enables a wide array of transformations, making it a valuable tool for chemists in both research and industry.
