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Specifications of 2-Pyridinol-1-oxide丨CAS 13161-30-3
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Appearance |
Yellow to brown powder |
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Assay (by Titration) |
98% min |
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Identification |
Meet the requirements |
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Melting point |
145 to 152℃ |
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Heavy metals |
20 ppm max |
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Water (by KF) |
0.5% max |
Transport Information of 2-Pyridinol-1-oxide丨CAS 13161-30-3
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2933790099 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tight closed, keep it in a cool and dry place. Air and light sensitive. |
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Condition to Avoid |
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Package |
25kg/drum, 1MT/pallet, or as requested |
Manufacturing Information of 2-Pyridinol-1-oxide丨CAS 13161-30-3
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Parameter |
Specification |
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Capacity |
60MT/year |
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Frequency |
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Main Export Countries |
EU, US, Japan, Korea |
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Capacity/Batch |
1-1.5MT |
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Experience |
Production since 2002 |
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Stock |
2MT |
Overview
2-Pyridinol-1-oxide丨CAS 13161-30-3, also known as 2-hydroxypyridine N-oxide, is a heterocyclic organic compound featuring a pyridine ring with an N-oxide functional group and a hydroxyl group at the 2-position. It exists in tautomeric equilibrium with 2-pyridone.
Applications
Chemical Intermediate
Used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals.
Serves as a building block for more complex heterocyclic compounds, often imparting biological activity.
Ligand in Coordination Chemistry
Acts as a bidentate ligand coordinating through oxygen and nitrogen atoms.
Employed in the design of metal complexes for catalysis, material science, and medicinal chemistry.
Catalyst or Catalyst Support
Utilized in catalysis for organic transformations, especially where metal-ligand cooperation is needed.
Can modify reactivity and selectivity of metal catalysts.
Pharmaceutical Research
The N-oxide group enhances water solubility and metabolic stability in drug design.
Explored as part of medicinal compounds with antimicrobial, antifungal, or anticancer potential.
Analytical Chemistry
Used in spectroscopic studies to understand tautomerism and hydrogen bonding.
Applied in mechanistic studies involving electron transfer and proton transfer.
Benefits
Versatile Reactivity
The dual nature of 2-Pyridinol-1-oxide丨CAS 13161-30-3 as both a Lewis base (through nitrogen) and an oxygen donor allows it to participate in diverse chemical reactions.
Improved Solubility and Stability
The N-oxide functionality enhances polarity and water solubility compared to pyridine, making it useful in aqueous-phase reactions.
Facilitates Metal Complex Formation
Its ability to chelate metals enables the design of catalysts with tailored properties and improved efficiency.
Tautomeric Flexibility
The equilibrium between N-oxide and hydroxypyridine forms allows for dynamic chemical behavior useful in synthetic and biological systems.
