2,5-Dibromopyridine丨CAS 624-28-2

2,5-Dibromopyridine丨CAS 624-28-2 is a halogenated heterocyclic compound used as an important intermediate in organic synthesis, particularly within pharmaceutical, agrochemical, and materials science sectors.
1. Pharmaceutical Intermediate
● Precursor for drug molecules: 2,5-Dibromopyridine丨CAS 624-28-2 serves as a building block in the synthesis of biologically active compounds, including anti-infectives, anti-inflammatory agents, and anticancer drug candidates.
● Functionalization: Its two bromine atoms allow for selective functionalization via cross-coupling reactions such as Suzuki, Heck, or Stille reactions, facilitating the creation of complex drug scaffolds.
2. Agrochemical Development
● Used in the production of herbicides, fungicides, and insecticides due to its reactive bromine substituents and heterocyclic core.
● Enables the design of pyridine-based active ingredients with tailored properties for pest control.
3. Materials Science
● Incorporated into the synthesis of organic electronic materials, such as:
o OLEDs (Organic Light-Emitting Diodes)
o Organic semiconductors
● The pyridine ring and bromine groups support the formation of conjugated systems or act as anchoring points for further modification.
4. Chemical Research and Development
● Widely used as a model compound in structure–activity relationship (SAR) studies.
● Serves as a substrate for testing novel catalytic systems in C–C and C–N bond-forming reactions.

● High reactivity: Dual bromine atoms at the 2 and 5 positions allow for versatile modification and tailored substitution patterns.
● Synthetic utility: Enables rapid construction of complex molecular frameworks, crucial for high-throughput screening and lead optimization.
● Commercial availability: Readily available and widely used in both academia and industry.
● Stability and shelf-life: Stable under standard storage conditions, making it practical for long-term laboratory use.