Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of 2-bromoacetophenone丨cas 70-11-1 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications of 2-Bromoacetophenone丨CAS 70-11-1
|
Appearance |
Light yellow to gray crystal |
|
Purity (GC) |
98% min |
|
Melting Point (MP) |
50~52℃ |
Transport Information of 2-Bromoacetophenone丨CAS 70-11-1
|
Parameter |
Specification |
|
UN Number |
2645 |
|
Class |
6.1 |
|
Packing Group |
II |
|
H.S. Code |
2914790090307 |
|
Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
|
Storage |
2~8 deg.C |
|
Condition to Avoid |
|
|
Package |
Applications of 2-Bromoacetophenone丨CAS 70-11-1
1. Intermediate in Organic Synthesis
Used extensively as an intermediate in the synthesis of various organic compounds, especially those containing α-bromo ketone functionality.
The bromine atom at the ortho position makes it highly reactive for nucleophilic substitution and coupling reactions.
2. Pharmaceuticals and Agrochemicals
Key building block for the synthesis of pharmaceutical agents and agrochemicals.
Utilized in the preparation of heterocyclic compounds and biologically active molecules.
3. Synthesis of Heterocycles
2-Bromoacetophenone丨CAS 70-11-1 acts as a precursor in the synthesis of heterocyclic compounds such as benzofurans, benzothiazoles, and indoles, which are important scaffolds in medicinal chemistry.
4. Formation of Carbon-Carbon Bonds
Participates in various coupling reactions (e.g., Suzuki, Stille, and Heck couplings) to introduce different substituents into aromatic systems.
Used in cross-coupling reactions due to the bromine atom's reactivity.
Benefits
1. Reactive Functional Groups
The combination of a ketone group and an ortho-bromo substituent offers dual reactivity, enabling diverse synthetic transformations.
The α-bromo ketone structure is a versatile handle for further functionalization.
2. Synthetic Versatility
Suitable for a wide range of reactions, including nucleophilic substitutions, cross-couplings, and cyclizations.
Facilitates the construction of complex molecular architectures.
3. Availability and Ease of Handling
Commercially available and relatively stable under recommended storage conditions, making it practical for laboratory and industrial use.
Summary
2-Bromoacetophenone丨CAS 70-11-1 is an important α-bromo ketone intermediate widely utilized in organic synthesis, pharmaceuticals, and agrochemicals. Its ortho-bromo substitution on acetophenone provides a reactive site for diverse transformations, including nucleophilic substitution and cross-coupling reactions, making it a versatile reagent for constructing complex molecules.
