2-Amino-5-iodopyridine丨CAS 20511-12-0

2-Amino-5-iodopyridine is primarily used as an intermediate in organic synthesis, pharmaceuticals, and agrochemical research. Its iodine and amino functionalities make it highly versatile for cross-coupling reactions, such as Suzuki or Sonogashira couplings, enabling the construction of complex heterocyclic and aromatic compounds. It is commonly employed in the synthesis of bioactive molecules, including kinase inhibitors, antiviral agents, and other pharmaceutical candidates. The compound is also used in the preparation of dyes, ligands for coordination chemistry, and functionalized heterocycles in material science, supporting both industrial applications and academic research.

The benefits of 2-Amino-5-iodopyridine include its high reactivity, selectivity in functionalization, and chemical stability. The iodine atom allows efficient halogen-based coupling reactions, while the amino group enables further derivatization and introduction of diverse substituents. Its structural features facilitate regioselective synthesis and high-yield transformations, making it suitable for multi-step chemical pathways. Additionally, the compound is stable under standard storage conditions, easy to handle, and compatible with a variety of solvents and reaction conditions, ensuring reproducible and efficient results in both laboratory and industrial settings.