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Specifications of Spiramycin丨8025-81-8
|
Property |
Specification |
|
Grade |
EP |
|
Characteristics |
White or slightly yellowish powder, slightly hygroscopic |
|
Assay |
4100 IU/mg (on dry basis) min |
|
Total |
90.0% min |
|
Identification |
Complies |
|
pH |
8.5 ~ 10.5 |
|
Specific Rotation |
-80.0° ~ -85.0° |
|
Spiramycin I |
80.0% min |
|
Spiramycin II |
5.0% min |
|
Spiramycin III |
10.0% min |
|
Total |
90.0% min |
|
Impurity A |
2.0% max |
|
Impurity B |
2.0% max |
|
Impurity C |
1.9% max |
|
Impurity D |
2.0% max |
|
Impurity E |
2.0% max |
|
Impurity F |
2.0% max |
|
Impurity G |
2.0% max |
|
Impurity H |
2.0% max |
|
Any Other Impurity |
2.0% max |
|
Total Impurities |
10.0% max |
|
Loss on Drying |
3.5% max |
|
Residue on Ignition |
0.1% max |
|
Acetic Acid |
5000 ppm max |
Transport Information of Spiramycin丨8025-81-8
|
Parameter |
Specification |
|
UN Number |
|
|
Class |
|
|
Packing Group |
|
|
H.S. Code |
2941907000999 |
|
Stability & Reactivity |
Stable |
|
Storage |
Tightly closed. Store in a closed, dry, ventilated place |
|
Condition to Avoid |
formation of dust and aerosols |
|
Package |
Manufacturing Information of Spiramycin丨8025-81-8
|
Parameter |
Specification |
|
Capacity |
10MT/month |
|
Frequency |
|
|
Main Export Countries |
|
|
Capacity/Batch |
|
|
Experience |
Production since 2003 |
|
Stock |
Introduction
Spiramycin丨8025-81-8 is a macrolide antibiotic derived from the bacterium Streptomyces spiramyceticus. It is primarily used for its antibacterial and antiparasitic properties, with applications in human medicine, veterinary care, and agriculture.
Applicatins of Spiramycin丨8025-81-8
1. Human Medicine
Treatment of Infections:
Used to treat respiratory infections, skin infections, and gastrointestinal infections, particularly those caused by Gram-positive bacteria.
Toxoplasmosis:
Often prescribed for the treatment of toxoplasmosis, especially in pregnant women to prevent fetal harm.
Alternative to Penicillin:
An alternative for patients allergic to penicillin or other antibiotics in the macrolide family.
2. Veterinary Medicine
Livestock Infections:
Applied in veterinary medicine to treat bacterial infections in livestock such as cattle, poultry, and pigs.
Prevention of Respiratory Diseases:
Used to treat or prevent respiratory diseases in animals caused by Mycoplasma and Pasteurella species.
3. Agriculture
Plant Protection:
Used as a fungicide and bactericide to control various plant pathogens.
Pest Control:
Applied for pest management in certain crops to protect against infections and diseases.
Benefits of Spiramycin丨8025-81-8
1. Broad-Spectrum Antimicrobial Action
Exhibits activity against a wide range of Gram-positive bacteria, parasites, and some Gram-negative bacteria.
2. Safe for Use in Pregnant Women
Spiramycin is considered safe for use during pregnancy for the treatment of toxoplasmosis, unlike many other antibiotics.
3. Alternative to Other Antibiotics
It serves as a second-line treatment for patients allergic to penicillin or when first-line antibiotics are ineffective.
4. Veterinary and Livestock Health
Enhances livestock health and productivity, reducing the need for more harmful chemicals.
5. Low Resistance Development
Reduced risk of developing resistance compared to other classes of antibiotics, making it useful in both human and veterinary medicine.
Conclusion
Spiramycin丨8025-81-8 is a versatile macrolide antibiotic used in human medicine, veterinary care, and agriculture for treating infections, managing diseases, and preventing pathogen growth. Its broad-spectrum activity, safety profile during pregnancy, and effectiveness in both humans and animals make it an essential drug for combating a variety of infections.
