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Specifications
| Appearance / Characteristics | White or almost white crystals |
| Identification | IR compliance with regulations |
| Appearance of solution | Clear and colorless |
| Assay | 99.0% - 101.0% |
| pH | 4.5 - 5.6 |
| Iron | 10 ppm max |
| Loss on drying | 0.5% max |
| Sulphated ash | 0.1% max |
| Heavy metals | 15 ppm max |
| Hydroquinone | 0.1% max |
| Unspecified impurities | 0.1% max |
| Total impurities | 0.2% max |
| Disregarded limit | 0.05% max |
Applications
Etamsylate (CAS 2624-44-4) is a hemostatic agent widely used in medicine to prevent and reduce bleeding. Clinically, it is applied in the treatment of capillary hemorrhages, menorrhagia, post-surgical bleeding, and trauma-induced bleeding. It is often formulated for oral, intravenous, or topical administration depending on the medical context. Etamsylate is also used in research to study hemostasis, vascular integrity, and platelet function, serving as a reference compound for the development of new anti-hemorrhagic therapies. Additionally, it finds applications in veterinary medicine to control bleeding in animals under surgical or trauma conditions.
Benefits
The benefits of etamsylate arise from its ability to enhance capillary resistance, improve platelet adhesion, and promote hemostasis without significantly affecting coagulation parameters. Unlike other hemostatic drugs, it does not increase the risk of thrombosis, making it safer for systemic use. It has rapid onset of action and is effective in reducing both minor and moderate bleeding episodes. Its water-soluble salt form improves bioavailability and ease of formulation for oral or injectable use. Moreover, etamsylate's safety profile, coupled with consistent efficacy, makes it suitable for both acute and preventive management of bleeding.
Conclusion
In summary, etamsylate is a hemostatic agent applied in clinical, research, and veterinary settings to prevent and control bleeding. Its applications include treatment of capillary hemorrhages, surgical bleeding, and menorrhagia, while its benefits lie in enhancing capillary integrity, improving platelet function, rapid efficacy, and a favorable safety profile. With these properties, etamsylate continues to be an essential therapeutic and research tool for managing bleeding disorders.
