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Specifications of Ertapenem Sodium丨CAS 153773-82-1
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Description |
White to light yellow powder |
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Assay |
90.0% min |
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Purity (HPLC) |
97.0% min |
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pH |
4.0 to 7.0 |
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Colour Level (ChP) |
NMT Y4 or YG4 |
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Water |
15.0% to 19.0% |
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Heavy metals |
20 ppm max |
Transport Information of Ertapenem Sodium丨CAS 153773-82-1
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
3003209000999 |
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Stability & Reactivity |
Stable under recommended storage conditions. |
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Storage |
Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -70 °C Store with desiccant. Air and light sensitive. |
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Condition to Avoid |
Air and light sensitive. |
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Package |
Manufacturing Information of Ertapenem Sodium丨CAS 153773-82-1
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Parameter |
Specification |
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Capacity |
50kg/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2014 |
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Stock |
Ertapenem Sodium丨CAS 153773-82-1 is the sodium salt form of ertapenem, a broad-spectrum carbapenem-class β-lactam antibiotic. It is used to treat a wide range of moderate to severe bacterial infections, especially those caused by Gram-positive and Gram-negative bacteria, including β-lactamase-producing strains.
Key Applications of Ertapenem Sodium丨CAS 153773-82-1
1. Treatment of Complicated Infections
Ertapenem Sodium丨CAS 153773-82-1 is FDA-approved and commonly used for treating:
● Complicated intra-abdominal infections
● Complicated urinary tract infections (UTIs)
● Skin and skin structure infections
● Acute pelvic infections
● Community-acquired pneumonia (CAP)
● Complicated gynecological infections
2. Prophylaxis in Colorectal Surgery
It is sometimes used as a single-dose preoperative prophylaxis in elective colorectal surgery to prevent postoperative infection due to its long half-life and wide coverage.
3. Hospital-Acquired and Resistant Pathogens
While not effective against Pseudomonas aeruginosa and Acinetobacter, it is highly effective against ESBL-producing Enterobacteriaceae, making it valuable for empirical therapy in resistant bacterial infections.
4. Once-Daily Dosing in Outpatient Settings
Due to its long half-life (~4 hours) and once-daily administration, Ertapenem is suitable for Outpatient Parenteral Antibiotic Therapy (OPAT), reducing hospital stays and healthcare costs.
Benefits of Ertapenem Sodium丨CAS 153773-82-1
✅ Broad Spectrum of Activity
● Active against a wide range of Gram-positive and Gram-negative bacteria, anaerobes, and β-lactamase producers.
● Covers many multi-drug resistant (MDR) organisms (excluding non-fermenters like P. aeruginosa).
✅ Convenient Dosing
● Once-daily intravenous (IV) or intramuscular (IM) administration makes it user-friendly and reduces caregiver burden.
✅ Effective Against ESBL-Producing Strains
● Ertapenem is often a drug of choice for infections caused by extended-spectrum β-lactamase (ESBL) producing bacteria.
✅ High Tissue Penetration
● Demonstrates excellent distribution in tissues, including peritoneal fluid, gynecologic tissues, and skin.
✅ Stable Against Most β-lactamases
● Remains effective where many penicillins and cephalosporins fail due to enzyme resistance.
Conclusion
Ertapenem Sodium丨CAS 153773-82-1 is a powerful, broad-spectrum antibiotic ideal for the treatment of various complicated bacterial infections. Its convenient once-daily dosing, robust activity against resistant pathogens, and broad clinical utility make it a cornerstone in both hospital and outpatient infection management. With proper stewardship, it remains a vital weapon against multidrug-resistant bacteria.

