Ertapenem Sodium丨CAS 153773-82-1

Ertapenem Sodium丨CAS 153773-82-1
Product Introduction:
Catalog No.: SS114555
CAS No.: 153773-82-1
Assay: 90.0%min; Purity(HPLC): 97.0%min.
Product Name: Ertapenem Sodium
Molecular Formula: C22H25N3O7S.Na
Molecular Weight: 498.51
Synonym(s): ertapenem monosodium
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Technical Parameters
Description

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Specifications of Ertapenem Sodium丨CAS 153773-82-1

 

Description

White to light yellow powder

Assay

90.0% min

Purity (HPLC)

97.0% min

pH

4.0 to 7.0

Colour Level (ChP)

NMT Y4 or YG4

Water

15.0% to 19.0%

Heavy metals

20 ppm max

 

Transport Information of Ertapenem Sodium丨CAS 153773-82-1

 

Parameter

Specification

UN Number

 

Class

 

Packing Group

 

H.S. Code

3003209000999

Stability & Reactivity

Stable under recommended storage conditions.

Storage

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -70 °C Store with desiccant. Air and light sensitive.

Condition to Avoid

Air and light sensitive.

Package

 

 

Manufacturing Information of Ertapenem Sodium丨CAS 153773-82-1

 

Parameter

Specification

Capacity

50kg/month

Frequency

 

Main Export Countries

 

Capacity/Batch

 

Experience

Production since 2014

Stock

 

Ertapenem Sodium丨CAS 153773-82-1 is the sodium salt form of ertapenem, a broad-spectrum carbapenem-class β-lactam antibiotic. It is used to treat a wide range of moderate to severe bacterial infections, especially those caused by Gram-positive and Gram-negative bacteria, including β-lactamase-producing strains.

 

Key Applications of Ertapenem Sodium丨CAS 153773-82-1

 

1. Treatment of Complicated Infections
Ertapenem Sodium丨CAS 153773-82-1 is FDA-approved and commonly used for treating:
● Complicated intra-abdominal infections
● Complicated urinary tract infections (UTIs)
● Skin and skin structure infections
● Acute pelvic infections
● Community-acquired pneumonia (CAP)
● Complicated gynecological infections
2. Prophylaxis in Colorectal Surgery
It is sometimes used as a single-dose preoperative prophylaxis in elective colorectal surgery to prevent postoperative infection due to its long half-life and wide coverage.
3. Hospital-Acquired and Resistant Pathogens
While not effective against Pseudomonas aeruginosa and Acinetobacter, it is highly effective against ESBL-producing Enterobacteriaceae, making it valuable for empirical therapy in resistant bacterial infections.
4. Once-Daily Dosing in Outpatient Settings
Due to its long half-life (~4 hours) and once-daily administration, Ertapenem is suitable for Outpatient Parenteral Antibiotic Therapy (OPAT), reducing hospital stays and healthcare costs.

 

Benefits of Ertapenem Sodium丨CAS 153773-82-1

 

✅ Broad Spectrum of Activity
● Active against a wide range of Gram-positive and Gram-negative bacteria, anaerobes, and β-lactamase producers.
● Covers many multi-drug resistant (MDR) organisms (excluding non-fermenters like P. aeruginosa).
✅ Convenient Dosing
● Once-daily intravenous (IV) or intramuscular (IM) administration makes it user-friendly and reduces caregiver burden.
✅ Effective Against ESBL-Producing Strains
● Ertapenem is often a drug of choice for infections caused by extended-spectrum β-lactamase (ESBL) producing bacteria.
✅ High Tissue Penetration
Demonstrates excellent distribution in tissues, including peritoneal fluid, gynecologic tissues, and skin.
✅ Stable Against Most β-lactamases
● Remains effective where many penicillins and cephalosporins fail due to enzyme resistance.

 

Conclusion

 

Ertapenem Sodium丨CAS 153773-82-1 is a powerful, broad-spectrum antibiotic ideal for the treatment of various complicated bacterial infections. Its convenient once-daily dosing, robust activity against resistant pathogens, and broad clinical utility make it a cornerstone in both hospital and outpatient infection management. With proper stewardship, it remains a vital weapon against multidrug-resistant bacteria.

 

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