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Specifications of Clindamycin hydrochloride丨CAS 21462-39-5
|
Grade |
USP43 |
|
Appearance |
White or almost white crystalline powder |
|
Assay |
800 µg/mg min |
|
Identification |
A) The IR spectrum of sample should be identical with that of reference standard. |
|
Crystalline |
Meets the requirements |
|
pH |
3.0 - 5.5 |
|
Water |
3.0% - 6.0% |
|
Lincomycin |
1.0% max |
|
Clindamycin B |
2.0% max |
|
7-Epiclindamycin |
4.0% max |
|
Any other individual related compounds |
≤ 1.0% max |
|
Total related compounds |
≤ 6.0% max |
|
Acetone |
5000 ppm max |
|
Ethanol |
5000 ppm max |
|
Chloroform |
60 ppm max |
Transport Information of Clindamycin hydrochloride丨CAS 21462-39-5
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Parameter |
Specification |
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UN Number |
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|
Class |
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|
Packing Group |
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|
H.S. Code |
2941904000999 |
|
Stability & Reactivity |
The following applies in general to flammable organic |
|
Storage |
Tightly closed. Store in a closed, dry, ventilated place |
|
Condition to Avoid |
Strong oxidizing agents |
|
Package |
Manufacturing Information of Clindamycin hydrochloride丨CAS 21462-39-5
|
Parameter |
Specification |
|
Capacity |
1MT/month |
|
Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2010 |
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Stock |
Applications of Clindamycin hydrochloride丨CAS 21462-39-5
1. Treatment of Bacterial Infections
Primarily used to treat serious infections caused by susceptible anaerobic bacteria and certain aerobic Gram-positive bacteria, including:
Respiratory tract infections
Skin and soft tissue infections
Bone and joint infections
Intra-abdominal infections
Pelvic inflammatory disease
Septicemia
Commonly prescribed for infections caused by Staphylococcus aureus, Streptococcus species, and Bacteroides fragilis.
2. Acne Treatment
Topical and oral forms of clindamycin hydrochloride are widely used to treat moderate to severe acne vulgaris due to its ability to reduce Propionibacterium acnes (now Cutibacterium acnes) colonization and inflammation.
3. Dental Infections
Used in dentistry to treat oral infections, periodontal disease, and as prophylaxis for bacterial endocarditis in patients allergic to penicillin.
4. Alternative for Penicillin-Allergic Patients
Serves as an important alternative antibiotic for patients allergic to beta-lactam antibiotics.
Benefits
✅ 1. Broad Antibacterial Spectrum
Effective against a wide range of anaerobic bacteria and many Gram-positive cocci, including some resistant strains.
✅ 2. Good Tissue Penetration
Excellent penetration into bone, soft tissues, and abscesses, making it suitable for treating deep-seated infections.
✅ 3. Versatile Formulations
Available in oral, topical, and parenteral (injectable) forms, allowing flexible use based on infection type and severity.
✅ 4. Well-Established Clinical Use
Decades of clinical use have established its efficacy, dosing regimens, and safety profile.
✅ 5. Anti-inflammatory Effects
Beyond antimicrobial activity, clindamycin exhibits anti-inflammatory properties useful in skin conditions such as acne.
Summary
Clindamycin hydrochloride丨CAS 21462-39-5 is a versatile and effective lincosamide antibiotic widely used to treat anaerobic and certain aerobic bacterial infections, acne, and dental infections. Its broad spectrum, good tissue penetration, and suitability for penicillin-allergic patients make it a valuable drug in clinical practice.
