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Specifications
| Grade | USP42/FCC11 |
| Appearance | White powder |
| Solubility (25°C) | Sparingly soluble in water; soluble in ethanol |
| Neotame content (on dry basis) | 97.0~102.0% |
| N-[N-(3,3-Dimethylbutyl)-L-alpha-Aspartyl]-L-Phenylalanine | 1.5% max |
| Other Related Substances | 2.0% max |
| pH, 0.5% solution | 5.0~7.0 |
| Water | 5.0% max |
| Sulfated ash | 0.2% max |
| Specific Rotation [α]20D, 0.5% solution, on dry basis | -40.0~-43.4 |
| Melting point | 81°C~84°C |
| Lead | 1 mg/kg max |
| Microbial Inspection Project | |
| Aerobic plate count | 250 cfu/g max |
| Escherichia coli | 10 cfu/g max |
| Yeasts and moulds | 100 cfu/g max |
| Salmonella | None Detected |
| Staphylococcus aureus | None Detected |
Applications
Neotame is a high-intensity, non-nutritive sweetener widely used in the food and beverage industry. It is incorporated into soft drinks, chewing gums, baked goods, dairy products, tabletop sweeteners, and low-calorie or sugar-free products due to its extreme sweetness potency, approximately 7,000–13,000 times that of sucrose. Neotame is valued for its stability under high-temperature processing and across a wide pH range, making it suitable for baking, pasteurization, and beverage production. It is also used in pharmaceuticals and dietary supplements as a flavor enhancer, masking bitter tastes in tablets, syrups, and nutritional formulations. Its intense sweetness allows manufacturers to achieve desired taste profiles at minimal usage levels, reducing caloric content without compromising flavor.
Benefits
The benefits of neotame stem from its high sweetness potency, stability, and safety profile. Being intensely sweet, only trace amounts are needed to achieve desired sweetness, which helps reduce caloric intake and supports sugar-free and low-calorie product development. Its stability under heat and acidic or basic conditions ensures that it maintains sweetness during processing, storage, and consumption. Neotame has a clean sweet taste without lingering aftertaste or bitterness, enhancing consumer acceptance in various foods and beverages. Additionally, it is suitable for people with diabetes or those managing blood sugar levels, as it does not significantly affect blood glucose. Its low usage levels also reduce production costs and formulation challenges compared to bulk sweeteners.
Conclusion
In summary, neotame is a high-intensity sweetener with applications in food, beverages, dietary supplements, and pharmaceuticals. Its benefits-including extreme sweetness, thermal and pH stability, clean taste, and low caloric contribution-make it an ideal ingredient for sugar-free and reduced-calorie formulations. By providing effective sweetness at minimal levels, neotame continues to play a crucial role in the development of healthier and more enjoyable food and beverage products.

