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Specifications
| Appearance | White to off-white crystalline powder or crystalline powder |
| Assay | 99% min |
| Specific optical rotation | 17.5 – 21.5° |
| Chloride | 0.07% max |
| Sulphate | 0.12% max |
| Heavy metal | 10 ppm max |
| Oxalic acid salt | 0.1% max |
| Bacterial endotoxin | 0.05 EU/mg max |
| Microbial limit | Total aerobic bacteria: 1000 cfu/g max; Total molds and yeasts: 100 cfu/g max; Escherichia coli: Not detected |
Applications
Calcium D-saccharate tetrahydrate is a calcium salt of D-glucaric acid widely used in pharmaceuticals, nutraceuticals, and food applications. In the pharmaceutical and dietary supplement industries, it is commonly incorporated into detoxification and liver-support formulations, as it has been studied for its ability to help the body eliminate carcinogens and toxins through the inhibition of β-glucuronidase. It is often included in combination products aimed at supporting hormone balance, liver health, and metabolic function. In food applications, calcium D-saccharate can serve as a source of calcium enrichment, contributing to nutritional fortification. Beyond health-related uses, it is also applied in biochemical and toxicological research as a reagent for studying glucuronidation pathways, which are central to drug metabolism and detoxification processes.
Benefits
The benefits of calcium D-saccharate tetrahydrate are centered on its health-promoting and biochemical properties. By inhibiting β-glucuronidase activity, it supports the body's natural detoxification systems, aiding in the removal of potentially harmful substances and excess hormones. This contributes to protective effects against certain toxin-related conditions and supports overall metabolic balance. As a source of calcium, it provides an additional nutritional benefit, contributing to bone health and physiological functions. Its safety profile and compatibility with a wide range of formulations make it suitable for supplements and fortified foods. In research, it offers scientists a reliable tool for studying metabolic and enzymatic processes, further enhancing its value in biomedical applications.
Conclusion
Calcium D-saccharate tetrahydrate (CAS 5793-89-5) is a versatile compound with important applications in health supplements, pharmaceuticals, food fortification, and biochemical research. Its detoxification-supporting properties, combined with its role as a calcium source, highlight its dual functional value in both preventive health and nutrition. With benefits including metabolic support, safety, and research relevance, it stands as a valuable ingredient for advancing health-promoting products and scientific understanding of detoxification pathways.

