Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of acetylleucine丨cas 99-15-0 in China. Welcome to wholesale custom made chemical products at competitive price from our factory. For more cheap products, contact us now.
Specifications
| Grade: | AJI92 |
| Appearance: | White crystals or crystalline powder |
| Assay: | 97.5–102.5% |
| Specific rotation [α]D20: | -1.0° ~ +1.0° |
| State of solution: | 95% min |
| Chloride (Cl): | 0.02% max |
| Ammonium (NH4): | 0.02% max |
| Sulfate (SO4): | 0.02% max |
| Iron (Fe): | 10 ppm max |
| Heavy metals (Pb): | 20 ppm max |
| Arsenic (As2O3): | 2 ppm max |
| Other amino acids: | Chromatographically not detectable |
| Loss on drying: | 0.5% max |
| Residue on ignition: | 0.30% max |
| pH: | 1.7–3.0 |
Applications
Acetylleucine is an N-acetylated derivative of the essential amino acid leucine, widely used in pharmaceutical research, neuropharmacology, and nutraceutical formulations. In medicine, it has been explored for its potential neuroprotective and cognitive-enhancing effects, particularly in the treatment of cerebellar ataxia and other neurodegenerative disorders. It is incorporated into clinical research as a therapeutic agent to improve motor coordination, balance, and neuronal function. In addition, acetylleucine serves as a biochemical tool in amino acid metabolism studies, helping to investigate leucine transport, acetylation processes, and the role of branched-chain amino acids in cellular physiology. Nutraceutical products sometimes include acetylleucine to support muscle function and overall neurological health.
Benefits
Acetylleucine offers multiple advantages due to its bioactive profile and enhanced pharmacokinetic properties compared to leucine. The acetylation increases its solubility, stability, and cellular uptake, allowing for more efficient transport across biological membranes, including the blood-brain barrier. This facilitates potential neuroprotective effects, improved motor function, and enhanced cognitive support. Additionally, it exhibits low toxicity and good tolerability, making it suitable for long-term therapeutic or supplemental use. In research, acetylleucine provides a reliable model for studying amino acid metabolism and the pharmacological effects of N-acetylated derivatives, contributing to drug development and nutritional sciences.
Conclusion
Acetylleucine is a versatile amino acid derivative with significant applications in neuropharmacology, clinical research, and nutraceuticals. Its neuroprotective potential, enhanced bioavailability, and safety profile make it a valuable compound for supporting motor coordination, cognitive function, and neurological health. Continued research and application of acetylleucine support its role in developing therapeutic interventions and functional nutritional products aimed at improving quality of life.
