N(alpha), N-(epsilon)-diacetyl-lysyl-alanyl-alanine丨CAS 24570-39-6

N(alpha), N-(epsilon)-diacetyl-lysyl-alanyl-alanine is a synthetic tripeptide derivative widely used in biochemical research, pharmaceutical development, and peptide synthesis studies. As an acetylated peptide, it serves as a model compound for studying post-translational modifications, particularly acetylation, which plays a crucial role in protein regulation and cellular signaling. It is often employed in enzymatic assays to investigate the activity of deacetylases and proteases, including lysine acetyltransferases (KATs) and histone deacetylases (HDACs). Furthermore, the compound is utilized in drug discovery programs focused on understanding peptide stability, metabolism, and bioavailability. Its well-defined structure and acetyl modifications also make it a valuable calibration standard in chromatographic and spectrometric peptide analyses.

N(alpha), N-(epsilon)-diacetyl-lysyl-alanyl-alanine offers multiple benefits owing to its stable, well-characterized tripeptide structure and dual acetylation. The acetyl groups protect reactive amine sites, enhancing peptide stability and resistance to enzymatic degradation during experimental or synthetic procedures. This feature allows precise control over peptide interactions and metabolic behavior, making it an excellent model for biological studies. It also helps researchers understand how acetylation influences protein conformation and function, thereby aiding in epigenetic and metabolic research. Additionally, its high purity and reproducibility ensure reliable analytical performance, whether used for method development, assay validation, or as a biochemical reference compound.