Mesitylene丨CAS 108-67-8

Mesitylene丨CAS 108-67-8, also known as 1,3,5-trimethylbenzene, is an aromatic hydrocarbon with the molecular formula C₉H₁₂. It appears as a colorless, flammable liquid with a sweet, pleasant odor and is characterized by three methyl groups symmetrically substituted on a benzene ring. Mesitylene is primarily used as a solvent, chemical intermediate, and fuel additive, thanks to its high boiling point, chemical stability, and symmetrical structure.

1. Solvent in Organic Synthesis and Industrial Processes
Mesitylene丨CAS 108-67-8 is widely employed as a non-polar solvent for:
● Catalytic reactions, including Friedel–Crafts alkylation and acylation.
● Polymerization reactions and Grignard reactions, due to its thermal stability and inertness.
● Extraction and purification processes, especially when high-boiling, aromatic solvents are required.
2. Intermediate in Dye, Resin, and Agrochemical Synthesis
It serves as a precursor in the manufacture of:
● Colorants and pigments, especially in the production of azo dyes.
● Polymeric resins, where mesitylene derivatives are incorporated into the resin backbone.
● Agrochemicals, including herbicide and pesticide synthesis via nitration or sulfonation reactions.
3. Fuel Additive
Used in gasoline blends to increase the octane number and enhance combustion efficiency. Its high calorific value and aromatic nature make it suitable for:
● Aviation fuels and performance-enhancing fuel additives.
● Reducing engine knock in internal combustion engines.
4. Research and Development
In laboratory settings, mesitylene is used as:
● A standard compound in NMR spectroscopy and chromatography.
● A reference aromatic solvent for studying electrophilic aromatic substitution reactions.

1. High Thermal and Chemical Stability
Mesitylene丨CAS 108-67-8 can withstand high temperatures without decomposing, making it suitable for high-temperature reactions and industrial processes.
2. Efficient Solvent Properties
Its low polarity and high solvency power for non-polar compounds make it a versatile solvent for organic reactions and coatings.
3. Symmetric Molecular Structure
The symmetrical placement of methyl groups allows predictable reactivity and clean substitution patterns, useful in chemical synthesis and modification.
4. Boosts Fuel Performance
As a high-octane additive, mesitylene enhances fuel quality, contributing to efficient combustion and reduced engine knocking in automotive and aviation fuels.