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Specifications of Disodium edetate dihydrate丨CAS 6381-92-6
|
Appearance: |
White crystalline powder |
|
Assay: |
99.5% min |
|
Cl: |
0.01% max |
|
SO4: |
0.05% max |
|
Fe: |
0.001% max |
|
Pb: |
0.001% max |
|
pH (50g/L, 25℃): |
4–5 |
|
NTA: |
0.1% max |
|
Chelating value: |
267 min |
Key Applications of Disodium edetate dihydrate丨CAS 6381-92-6
1. Chelating Agent in Pharmaceuticals
● Used to stabilize pharmaceutical formulations by binding to trace metal ions (like Fe²⁺, Cu²⁺), preventing oxidation and degradation of sensitive ingredients.
● Helps enhance drug stability and shelf life.
● Included in:
oInjectable solutions
oOphthalmic drops
oOral and topical medicines
2. Food Additive & Preservative
● Recognized as a sequestrant under the code E386.
● Binds metal ions that can catalyze food oxidation and spoilage, especially in:
oCanned vegetables
oDressings and sauces
oBeverages (to protect color and flavor)
3. Cosmetics and Personal Care Products
● Commonly found in:
oShampoos and conditioners
oCreams and lotions
oMouthwash and toothpaste
● Functions:
oStabilizes formulations by sequestering metal ions
oImproves product clarity and shelf stability
4. Industrial and Laboratory Uses
● Employed in:
oWater treatment to soften water by binding calcium and magnesium
oLaboratory buffers for biochemical and molecular biology experiments
oCleaning solutions for removing metal residues
oPhotographic industry to prevent metal-induced image fogging
5. Agriculture
● Used in micronutrient formulations as a chelating agent for trace metals like iron and zinc, making them more bioavailable for plant uptake.
Benefits of Disodium edetate dihydrate丨CAS 6381-92-6
√ Powerful Chelating Action
Binds with a wide range of metal ions, reducing their reactivity and preventing unwanted chemical changes.
√ Water Solubility
Highly soluble in water, making it easy to incorporate into aqueous formulations.
√ Multifunctionality
One compound serves multiple purposes: preservation, stabilization, and enhanced performance of other ingredients.
√ Non-toxic at Low Concentrations
Generally regarded as safe (GRAS) in regulated doses, especially in food and personal care applications.
Conclusion
Disodium edetate dihydrate丨CAS 6381-92-6 is a versatile and effective chelating agent widely used in pharmaceuticals, food, cosmetics, and industrial processes. By stabilizing formulations and preventing metal-catalyzed degradation, it plays a critical role in enhancing product quality, safety, and longevity across various sectors. Its water solubility, safety profile, and broad applicability make it a key additive in both consumer and industrial formulations.

