Tetrasodium Glutamate Diacetate丨CAS 51981-21-6

Tetrasodium Glutamate Diacetate丨CAS 51981-21-6 is a biodegradable, NTA- and EDTA-alternative chelating agent used widely in personal care, cleaning, and industrial applications due to its excellent metal ion binding capabilities and environmental safety.

1. Home and Industrial Cleaning Products
a. Chelating Agent in Detergents
Tetrasodium Glutamate Diacetate丨CAS 51981-21-6 is used in household and industrial cleaning products such as:
● Dishwashing detergents
● Laundry detergents
● Surface cleaners
● Hard surface descalers
Its role is to bind metal ions (e.g., calcium, magnesium, iron) that interfere with cleaning processes by causing deposits or reducing surfactant effectiveness.
b. Hard Water Tolerance
Tetrasodium glutamate diacetate enhances cleaning performance in hard water, preventing limescale formation and improving the stability and efficacy of surfactants.
2. Personal Care and Cosmetic Products
Used in:
● Shampoos and conditioners
● Liquid soaps and body washes
● Facial cleansers and lotions
As a chelating agent, it improves product stability, preservative efficacy, and foam performance, especially in the presence of divalent metal ions.
3. Agricultural and Horticultural Applications
GLDA-Na4 is used to chelate micronutrients (e.g., Fe, Zn, Cu, Mn) in fertilizers, improving:
● Nutrient solubility
● Uptake by plants
● Stability in foliar sprays and hydroponic solutions
It is often preferred over EDTA for its biodegradability and eco-friendliness.
4. Industrial Applications
a. Metalworking and Descaling
Used in metal surface cleaning, scale removal, and passivation processes where removal of scale or rust requires effective chelation of metal ions.
b. Oil & Gas Industry
GLDA is applied in enhanced oil recovery and well stimulation, where it helps remove scale and improve flow in the presence of metal-containing mineral deposits.
5. Food Industry (in Some Regions)
In certain jurisdictions, it may be used as a food-grade chelating agent to stabilize color and texture by binding trace metal ions, though its approval varies by region.

1. Excellent Biodegradability
One of GLDA's most significant advantages over traditional chelating agents like EDTA or NTA is its readily biodegradable nature (OECD 301 test). This makes it suitable for green formulations and environmentally-conscious applications.
2. High Chelation Efficiency
It demonstrates effective chelation over a wide pH range, particularly in alkaline formulations (pH 4–10), which makes it highly versatile for different applications including cleaning, cosmetics, and industrial processes.
3. Safer Alternative to Traditional Chelators
● Non-toxic: Low oral and dermal toxicity
● Non-irritating: Mild on skin and eyes
● No carcinogenic concerns: Unlike some alternatives such as NTA
This makes GLDA safer for consumers, workers, and the environment.
4. Improved Formulation Stability
GLDA stabilizes emulsions, preservatives, and surfactants in formulations by preventing metal ion-induced degradation. This results in longer shelf life and improved product performance.
5. Compatibility
Compatible with a broad range of:
● Surfactants (anionic, nonionic, amphoteric)
● Preservatives
● Fragrances
● Enzymes
● Organic and inorganic acids
This makes it an excellent formulation component in complex blends.
6. Sustainably Sourced
GLDA is often derived from renewable feedstocks (e.g., glutamic acid from plant or microbial fermentation), further enhancing its sustainability profile.

Tetrasodium Glutamate Diacetate丨CAS 51981-21-6 is a safe, effective, and environmentally friendly chelating agent ideal for use in cleaning, personal care, agriculture, and industrial applications. It offers strong performance in hard water conditions, enhances the stability and efficacy of formulations, and serves as a sustainable alternative to traditional, less eco-friendly chelators like EDTA. Its biodegradability, low toxicity, and broad compatibility make it a preferred ingredient in both consumer and industrial products aligned with modern environmental and safety standards.