Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of n-(4-(4-fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-n-methylmethanesulfonamide丨cas 147118-37-4 in China. Welcome to wholesale custom made chemical products at competitive price from our factory. For more cheap products, contact us now.
Specifications
| Description | Off-white or white crystalline powder |
| Purity | 98% min |
| Identification | HPLC |
| Water | 0.5% max |
| Impurity (Total) | 2.0% max |
Transport Information
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H.S. Code |
2935900090303 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Keep container tightly closed. Store in a cool and shaded area. Keep under inert gas. |
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Condition to Avoid |
Exposure to air |
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Package |
Manufacturing Information
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Capacity |
10MT/year |
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Experience |
Production since 2012 |
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Stock |
Applications
N-(4-(4-Fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide is primarily utilized as an intermediate in pharmaceutical research and drug development. It is used in the synthesis of novel pyrimidine-based compounds, which are important scaffolds in medicinal chemistry due to their diverse biological activities. This compound serves as a building block for the design and optimization of potential therapeutic agents, particularly targeting cancer, inflammation, and infectious diseases. Additionally, it may be employed in structure-activity relationship (SAR) studies to develop drugs with enhanced efficacy and selectivity.
Benefits
The compound's pyrimidine core, combined with fluorophenyl and sulfonamide groups, provides a versatile platform for chemical modifications, allowing fine-tuning of pharmacokinetic and pharmacodynamic properties. The presence of the formyl group offers a reactive site for further derivatization, facilitating the synthesis of a wide range of analogs. The fluorine atom enhances metabolic stability and membrane permeability, often improving drug-like properties. Overall, this compound supports efficient lead optimization, accelerating the development of potent and selective drug candidates.
Conclusion
N-(4-(4-Fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide is a valuable intermediate in medicinal chemistry, enabling the creation of diverse pyrimidine derivatives with promising therapeutic potential. Its structural features and chemical reactivity make it an important tool in drug discovery and pharmaceutical innovation.
