4-Ethoxycarbonylphenylboronic Acid丨CAS 4334-88-7

4-Ethoxycarbonylphenylboronic acid is an important organoboron compound widely used in organic synthesis, pharmaceutical research, and material science. It serves as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the construction of biaryl and heteroaryl compounds, which are essential scaffolds in drug discovery, agrochemical development, and fine chemical synthesis. The ethoxycarbonyl group offers additional reactivity, allowing further functionalization such as hydrolysis, amide formation, or ester transformations. This compound is also utilized in the synthesis of fluorescent dyes, ligands, and functional materials where boronic acid groups facilitate molecular assembly, sensing applications, or binding interactions with diols and sugars.

The compound provides significant advantages due to its high reactivity, stability, and functional versatility. The boronic acid moiety enables efficient and selective formation of carbon–carbon bonds under mild conditions, while the ethoxycarbonyl substituent allows for diverse chemical transformations and fine-tuning of molecular properties. Its crystalline nature and good shelf stability ensure ease of handling, storage, and reproducibility in multi-step syntheses. Additionally, the compound is compatible with a variety of catalysts, solvents, and reaction conditions, allowing high yields and scalability. These characteristics make it a valuable building block in both research and industrial applications.