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Specifications
| Appearance: | Off white crystalline powder |
| Purity (HPLC): | 99% min |
| Burning residue: | 5000 ppm max |
| Water: | 2000 ppm max |
Transport Information
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Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2916399090305 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place |
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Condition to Avoid |
Oxidizing agents |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
1MT/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2021 |
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Stock |
Applications
1. Intermediate in Organic Synthesis
Widely used as a building block in the synthesis of:
Liquid crystals
Agrochemicals
Pharmaceuticals
Dyes and optical brighteners
Its rigid biphenyl structure makes it ideal for constructing planar, aromatic systems.
2. Liquid Crystal Materials
Acts as a mesogenic core or spacer in liquid crystal compounds.
The rigid, planar biphenyl ring system and the polar carboxylic group contribute to the alignment and thermal stability of liquid crystal displays (LCDs).
3. Polymer and Resin Manufacturing
Used in the synthesis of polyesters, polyamides, and polyimides.
Incorporating 4-biphenylcarboxylic acid imparts mechanical strength, thermal stability, and rigidity to the resulting polymers.
4. Medicinal Chemistry and Drug Design
A useful intermediate for making aryl-substituted carboxylic acids, NSAID analogs, or other aryl carboxylic acid-containing pharmacophores.
Can be used in SAR studies or ligand development.
5. Metal Complexation and Coordination Chemistry
Carboxylate group can act as a ligand to form metal-organic frameworks (MOFs) or coordination polymers, with potential applications in:
Gas storage
Catalysis
Sensing
Benefits
1. Structural Rigidity and Planarity
The biphenyl unit contributes rigidity and conjugation, useful in designing molecules with defined geometries and electronic properties.
2. Modifiable Functional Group
The carboxylic acid group allows for further derivatization:
Esterification
Amidation
Salt formation
Enables tailored functionality in polymers, pharmaceuticals, and advanced materials.
3. High Purity and Commercial Availability
Available in high-purity grades, making it suitable for electronic, optical, and pharmaceutical applications.
Well-characterized and stable under standard conditions.
4. Compatibility with Coupling Reactions
Can undergo Suzuki, Heck, or Ullmann reactions at the biphenyl core.
Ideal for synthesizing more complex aryl architectures.
Conclusion
4-Biphenylcarboxylic acid (CAS 92-92-2) is a versatile and widely used aromatic carboxylic acid with a rigid biphenyl backbone. It serves as a key intermediate in the synthesis of liquid crystals, pharmaceuticals, functional polymers, and coordination materials. Its planarity, modifiability, and thermal stability make it highly valuable in both research and industrial applications.
