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Specifications
| Appearance: | white crystal or powder |
| Assay: | 98%min |
| MP: | 367 to 370 deg C |
| Water: | 0.5%max |
| Volatile: | 0.4%max |
| Hg: | 785ppm |
Transport Information
|
Parameter |
Specification |
|
UN Number |
2585 |
|
Class |
8 |
|
Packing Group |
III |
|
H.S. Code |
2933310090999 |
|
Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
|
Storage |
Tightly closed. Store in a closed, dry, ventilated place |
|
Condition to Avoid |
|
|
Package |
Applications
1. Pharmaceutical Intermediate
Commonly used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs).
Its sulfonic acid group imparts water solubility and reactivity, useful for attaching to various pharmacophores.
2. Catalysis and Organocatalysts
Serves as a ligand or co-catalyst in transition metal-catalyzed reactions due to its nitrogen and sulfonic acid functional groups.
Enhances solubility and electron-withdrawing characteristics in acid-catalyzed organic transformations.
3. Dye and Pigment Industry
Used in the manufacture of azo dyes, where it acts as a coupling component or modifying agent to increase water solubility and brightness.
4. Polymer Modification
Can be incorporated into functionalized polymers to introduce acidic sites for ion exchange resins, membrane materials, or proton-conducting materials.
5. Analytical Chemistry
Used in derivatization reactions or as a matrix modifier in techniques such as chromatography or mass spectrometry.
Benefits
1. Dual Functional Groups
Contains both a basic nitrogen (from the pyridine ring) and a strong acidic sulfonic group, offering versatile reactivity.
Useful in bifunctional applications such as acid-base catalysis or ionic compound synthesis.
2. High Water Solubility
Sulfonic acid group ensures excellent solubility in aqueous media, which is beneficial in pharmaceutical formulations or water-based industrial processes.
3. Stable Under a Wide pH Range
Chemically robust, maintaining structural integrity in both acidic and basic environments.
4. Structural Versatility
The 3-position substitution on pyridine allows for unique spatial and electronic properties, useful for selective reactions or as a building block in heterocyclic compound synthesis.
Conclusion
3-Pyridinesulfonic acid (CAS 636-73-7) is a multifunctional organic compound widely employed as an intermediate, reactive modifier, and ligand in several industrial and research contexts. Its combination of a heteroaromatic ring and a sulfonic acid group enables diverse applications across pharmaceuticals, catalysis, dye chemistry, and polymer science. With its water solubility, chemical stability, and functional versatility, it remains a valuable tool in both synthetic and applied chemistry.
