Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of kanamycin sulfate丨cas 25389-94-0 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications
| Grade | CP2000 / BP2025 |
| Appearance | White or off-white crystalline powder |
| Solubility | Complies |
| Identification (IR, HPLC) | Complies |
| Reactions of Sulfates | Complies |
| Solutions | Complies |
| Specific rotation | +116 ~ +123° |
| Loss on drying | 1.5% max |
| Kanamycin B | 2.0% max |
| Residue on ignition | 0.5% max |
| Sulfate | 15.0% ~ 17.0% |
| Sulphate ash | 0.5% max |
| Pyrogens | Complies |
| Abnormal Toxicity | Complies |
| Bacterial Endotoxin | 0.4 EU/mg max |
| Potency (Calculated by dry product) | 765 u/mg min |
| Potency (Calculated by wet product) | 760 u/mg min |
Applications
Kanamycin sulfate is a broad-spectrum aminoglycoside antibiotic widely used in microbiology, pharmaceutical research, and biotechnology. It is primarily applied for the treatment and prevention of bacterial infections caused by Gram-negative and certain Gram-positive organisms. In laboratory and industrial biotechnology, kanamycin sulfate is extensively used as a selective agent in molecular biology, particularly for maintaining plasmids carrying kanamycin resistance genes in bacterial cultures. It is a standard component in recombinant DNA technology, protein expression systems, and microbial fermentation processes. In pharmaceutical development, kanamycin sulfate is used in formulation research, quality control testing, and antimicrobial activity evaluation. It is also applied in veterinary medicine and in studies related to antibiotic resistance, microbial physiology, and drug screening.
Benefits
The benefits of kanamycin sulfate arise from its strong antibacterial activity, reliability as a selection marker, and well-characterized pharmacological profile. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, leading to effective suppression of susceptible microorganisms. In molecular biology applications, it provides consistent and robust selection pressure, ensuring stable maintenance of recombinant plasmids and expression vectors. The sulfate salt form enhances water solubility and stability, facilitating easy preparation of sterile solutions and accurate dosing. Kanamycin sulfate demonstrates good stability under recommended storage conditions and compatibility with common culture media and buffers. Its established safety and efficacy profile support reproducible results in both clinical and research environments.
Conclusion
Kanamycin sulfate is a versatile and widely used antibiotic with significant value in medical treatment, biotechnology, and microbiological research. Its potent inhibition of bacterial protein synthesis, excellent solubility, and reliability as a genetic selection agent make it an essential tool in modern life science and pharmaceutical applications. By supporting effective infection control, stable recombinant systems, and antimicrobial research, kanamycin sulfate continues to play a critical role in healthcare and biotechnology development.
