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Specifications of Chlortetracycline hydrochloride丨CAS 64-72-2
|
Grade |
EP10 |
|
Appearance |
Yellow powder |
|
Identification |
A: Thin layer chromatography |
|
pH |
2.3～3.3 |
|
Specific optical rotation |
-235～-250 |
|
Absorbance |
0.4 max |
|
Heavy metals |
50 ppm max |
|
Water |
2.0% max |
|
Sulphated Ash |
0.5% max |
|
Impurity A |
4.0% max |
|
Impurity B |
1.0% max |
|
Impurity C |
1.0% max |
|
Impurity D |
0.3% max |
|
Impurity G |
0.2% max |
|
Impurity H |
0.2% max |
|
Impurity L |
0.2% max |
|
Impurity K |
0.2% max |
|
Unspecified Impurities |
0.1% max |
|
Sum of impurities other than A |
2.0% max |
|
CTC: HCl (anhydrous substance) |
89.5% min |
|
TC.HCl (anhydrous substance) |
6.0% max |
|
CTC.HCl + TC.HCl (anhydrous substance) |
94.5% ～ 102.0% |
|
Residual ethanol |
0.5% max |
|
Proteins |
2.0% max |
|
Crude fiber |
0.1% max |
Transport Information of Chlortetracycline hydrochloride丨CAS 64-72-2
|
Parameter |
Specification |
|
UN Number |
|
|
Class |
|
|
Packing Group |
|
|
H.S. Code |
2941302000999 |
|
Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
|
Storage |
Inert atmosphere, Store in freezer, under -20°C |
|
Condition to Avoid |
|
|
Package |
Applications of Chlortetracycline hydrochloride丨CAS 64-72-2
1. Antibacterial Agent
Used as a broad-spectrum antibiotic effective against a wide variety of Gram-positive and Gram-negative bacteria.
Commonly prescribed in both human and veterinary medicine to treat infections such as respiratory tract infections, urinary tract infections, and skin infections.
2. Veterinary Medicine
Widely used in animal husbandry to prevent and treat infections in livestock and poultry.
Also employed as a growth promoter in some animal feeds (though this use is regulated or restricted in many countries due to antibiotic resistance concerns).
3. Agricultural Applications
Used in plant agriculture to control bacterial diseases such as fire blight in apples and pears.
4. Research and Pharmaceutical Manufacturing
Utilized in the synthesis and study of antibiotic derivatives.
Used as a reference compound in microbiological assays and antibiotic resistance studies.
Benefits
✅ Broad-Spectrum Efficacy
Effective against many bacterial strains, including those causing common infections.
✅ Multiple Routes of Administration
Can be administered orally, topically, or by injection, providing versatility in treatment options.
✅ Well-Studied and Established
One of the first tetracycline antibiotics discovered, with a long history of clinical use and extensive safety data.
✅ Synergistic Effects
Sometimes used in combination with other antibiotics or agents to enhance antimicrobial activity.
Summary
Chlortetracycline hydrochloride丨CAS 64-72-2 is a widely used broad-spectrum tetracycline antibiotic with applications in human and veterinary medicine, agriculture, and pharmaceutical research. Its effectiveness against a range of bacterial infections and established safety profile make it a valuable antimicrobial agent, though careful use is essential to minimize resistance development.
