Calcium Pantothenate丨CAS 137-08-6

Calcium pantothenate丨CAS 137-08-6, the calcium salt of pantothenic acid (vitamin B5), is a water-soluble vitamin widely used in pharmaceuticals, animal nutrition, cosmetics, and food fortification. Known for its essential role in coenzyme A synthesis and metabolic function, it is a critical nutrient across human health, veterinary use, and industrial formulations.

Applications

1. Pharmaceuticals & Dietary Supplements

Calcium pantothenate丨CAS 137-08-6 is extensively used in:

Multivitamin formulations to ensure adequate intake of vitamin B5.

Therapeutic supplements for managing deficiencies in patients with malnutrition, chronic illnesses, alcoholism, or gastrointestinal disorders.

Injection preparations (in certain countries) for faster delivery in clinical settings.

2. Animal Nutrition

Calcium pantothenate is a core ingredient in animal feed premixes for:

Poultry, swine, cattle, and aquaculture species.

Enhancing growth rate, feed conversion ratio, and reproductive performance.

Preventing symptoms of deficiency such as dermatitis, growth retardation, and gastrointestinal issues.

It is often added in premixed feeds, concentrates, and mineral supplements, especially for:

Broilers: improves feathering and skin condition.

Breeding animals: supports fertility and embryo development.

3. Food Fortification

In the food industry, calcium pantothenate is approved as a vitamin B5 fortifier in:

Breakfast cereals

Beverages (energy and sports drinks)

Nutrition bars

Infant formulas

Processed foods

Fortifying food with calcium pantothenate ensures population-level access to adequate vitamin B5, especially in regions where dietary intake is insufficient.

4. Cosmetics and Skincare

Thanks to its moisturizing and skin-repairing properties, calcium pantothenate (and its derivative panthenol) is used in:

Facial creams

Anti-aging formulations

Hair conditioners

After-sun products

Acne treatments

It helps:

Improve skin elasticity

Maintain hydration

Promote wound healing

Soothe irritation and redness

Benefits

1. Supports Energy Metabolism

Calcium pantothenate丨CAS 137-08-6 plays a vital role in the synthesis of coenzyme A (CoA) and acyl carrier protein (ACP), which are critical in:

Fatty acid metabolism

Carbohydrate and protein metabolism

Energy production (via the Krebs cycle)

By enabling efficient nutrient breakdown, it helps maintain stamina, mental focus, and general vitality.

2. Promotes Healthy Skin and Hair

Vitamin B5 improves:

Wound healing and skin regeneration

Sebum regulation, reducing acne flare-ups

Hair strength and moisture retention, supporting growth and reducing breakage

This makes it a go-to ingredient in personal care and therapeutic dermatology.

3. Reduces Stress and Enhances Mood

Vitamin B5 is essential in synthesizing adrenal hormones like cortisol, helping the body respond to physical and emotional stress. Adequate intake may:

Improve mental clarity

Reduce fatigue

Support emotional resilience

4. Enhances Immune Function

Pantothenic acid contributes to:

The synthesis of antibodies

Production of coenzymes that support immune cell function

Overall immune regulation

Its inclusion in daily nutrition can help maintain resistance to infections and promote recovery.

5. Supports Cardiovascular and Neurological Health

By supporting:

Lipid metabolism, it may help manage cholesterol levels.

Neurotransmitter synthesis, including acetylcholine - vital for memory and muscle control.

Myelin sheath formation, protecting nerve fibers and supporting nerve conduction.

6. Essential for Fetal Development

In prenatal care, calcium pantothenate supports:

Embryonic growth

Nervous system development

Maternal energy metabolism

It is often included in prenatal vitamins to ensure proper fetal development and reduce the risk of birth defects.

Conclusion

Calcium pantothenate is a versatile, essential compound that plays key roles in human and animal health, energy metabolism, immune function, dermatology, and nutritional science. Its benefits span from promoting physical vitality and stress resistance to enhancing skin health and fertility. Because of its stability and bioavailability, it remains the preferred form of vitamin B5 in many commercial and therapeutic applications.