Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of benfotiamine丨cas 22457-89-2 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications
| Description | White crystal or white crystalline powder |
| Assay | 98% ~ 102% |
| Identification | The retention time of main peak is accordant with that of Benfotiamine RS |
| Melting point | 198℃ min |
| Loss on drying | 1.2% max |
| Clarity and color of solution | Colorless to light yellow clear solution |
| Chloride | 0.053% max |
| Sulphate | 0.011% max |
| Heavy metals | 20 ppm max |
| Cd | 1 ppm max |
| As | 1 ppm max |
| Pb | 0.5 ppm max |
| Hg | 0.3 ppm max |
| Bulk density | 0.35 g/ml min |
| Thiamine | 0.1% max |
| Benzoic acid | 0.1% max |
| Total impurities | 1% max |
| Total Plate Count | 1000 cfu/g max |
| Yeast & Mold | 100 cfu/g max |
| Salmonella | Negative |
| E.Coli | Negative |
| Staphylococcus Aureus | Negative |
Applications
Benfotiamine is a fat-soluble derivative of thiamine (vitamin B1) widely applied in the pharmaceutical and nutraceutical industries. It is commonly used in dietary supplements for the management of diabetic complications such as neuropathy, retinopathy, and nephropathy, as it helps regulate advanced glycation end products (AGEs). In clinical practice, it is applied to improve nerve health, support metabolic processes, and enhance glucose metabolism. Beyond diabetes care, Benfotiamine is used in formulations aimed at cardiovascular protection, antioxidant support, and overall neurological wellness.
Benefits
The benefits of Benfotiamine stem from its enhanced bioavailability compared to thiamine, allowing it to penetrate cell membranes more effectively. This leads to improved therapeutic outcomes in preventing and alleviating oxidative stress, nerve damage, and endothelial dysfunction. It helps reduce harmful byproducts of glucose metabolism, thereby protecting tissues from long-term damage. In addition, its neuroprotective and antioxidant properties contribute to better cognitive health, reduced inflammation, and overall improved metabolic resilience.
Conclusion
Benfotiamine serves as a highly effective thiamine derivative with important applications in diabetes management, nerve protection, and overall metabolic health. Its superior absorption and wide range of biological benefits make it a valuable compound in both medical and nutritional fields, contributing to better prevention and management of chronic conditions.
