Calcium Dihydrogenphoshate丨CAS 7758-23-8

Calcium dihydrogenphoshate丨7758-23-8, also known as calcium hydrogen phosphate or monocalcium phosphate (MCP), is an inorganic chemical compound with the CAS number 7758-23-8. It is commonly encountered as a white crystalline powder or in granular form. The chemical formula for calcium dihydrogen phosphate is Ca(H₂PO₄)₂·H₂O, indicating that the compound is a hydrated form of calcium phosphate. It plays an essential role in various applications, particularly in the fields of agriculture, pharmaceuticals, and animal nutrition.

Calcium dihydrogen phosphate is produced primarily through the reaction of phosphoric acid (H₃PO₄) with calcium carbonate (CaCO₃) or calcium hydroxide (Ca(OH)₂). It is an important source of both calcium and phosphorus, two essential nutrients for plant and animal growth.

1. Animal Feed and Nutrition
One of the most significant applications of calcium dihydrogen phosphate is in the animal feed industry. It serves as a highly bioavailable source of calcium and phosphorus, two key minerals essential for bone development, energy production, and overall health in animals.
● Supplement in Livestock Feed: Monocalcium phosphate is widely used as a mineral supplement in the diets of livestock, including poultry, swine, cattle, and aquatic species. It provides animals with the necessary calcium and phosphorus for strong bone growth, reproduction, and metabolic functions.
● Improvement of Growth and Productivity: By supplementing animal feed with calcium dihydrogen phosphate, farmers can promote faster growth, better feed conversion ratios, and enhanced reproductive health in animals.
2. Fertilizers and Agriculture
Calcium dihydrogenphoshate丨7758-23-8 is also used in the fertilizer industry, particularly in the production of phosphate-based fertilizers. Phosphorus is a critical nutrient for plant growth, and its availability is crucial for crop yields.
● Source of Phosphorus for Plants: In agriculture, calcium dihydrogen phosphate acts as a slow-release source of phosphorus, which is essential for promoting root development, flowering, and fruiting in plants. The calcium content also helps improve soil structure and prevent soil acidification.
● Soil Amendment: The addition of calcium dihydrogen phosphate to the soil improves the availability of phosphorus to plants, especially in soils with low phosphorus content. It is often used in fertilizer blends to enhance crop productivity and ensure healthy plant growth.
3. Food and Beverage Industry
Calcium dihydrogen phosphate finds some application in the food and beverage industry, particularly in baking powders and as a food additive.
● Leavening Agent in Baking: Monocalcium phosphate is used in the production of baking powders as a leavening agent. When mixed with sodium bicarbonate, it produces carbon dioxide gas, which causes doughs and batters to rise, giving baked goods their light, fluffy texture.
● Food Additive: It can also be used as a calcium fortifier in food products. It is sometimes added to fortified cereals, dairy products, and beverages to enhance the calcium content of the food, thereby helping to meet nutritional requirements for calcium.
4. Pharmaceutical and Health Supplements
Calcium dihydrogen phosphate is utilized in the pharmaceutical industry due to its calcium content, which is vital for bone health and metabolic functions.
● Calcium Supplement: It is sometimes included in dietary supplements and multivitamin tablets as a source of calcium. Since calcium is essential for bone health, nerve function, and muscle contraction, calcium dihydrogen phosphate can help address calcium deficiencies in individuals who may not receive sufficient calcium from their diet.
● Formulation of Pharmaceutical Compounds: The compound is used in the formulation of antacids and oral rehydration salts (ORS), as it helps balance calcium and phosphate levels in the body. It is also utilized as a pharmacological excipient in the formulation of tablets and capsules.
5. Industrial Applications
In addition to its biological and agricultural applications, calcium dihydrogen phosphate is used in various industrial processes.
● Water Treatment: Calcium dihydrogen phosphate is sometimes used in water treatment processes to remove impurities or adjust pH levels. It can help in the treatment of drinking water, wastewater, and in industrial applications where water chemistry needs to be controlled.
● Paint and Coating Industry: It is used in the formulation of certain coatings and paints as a phosphate source, helping to improve the durability and corrosion resistance of the final product.
6. Research and Laboratory Use
In scientific research, Calcium dihydrogenphoshate丨7758-23-8 is often employed as a reagent or in the preparation of phosphate-buffered solutions.
● Buffer Solution: It is used in the preparation of phosphate-buffered saline (PBS), a commonly used buffer solution in biological and biochemical research. These solutions maintain a stable pH and are crucial in cell culture and molecular biology applications.

1. Supports Animal Health and Growth
Calcium dihydrogen phosphate provides a highly bioavailable source of both calcium and phosphorus, two essential minerals for bone formation, muscle function, and overall growth in animals. By supplementing animal feed with this compound, it enhances growth rates, reproductive efficiency, and feed utilization, making it an essential component in livestock farming.
● Bone Health: Calcium and phosphorus are critical for maintaining strong, healthy bones in animals. By ensuring that animals have access to an adequate supply of these minerals, calcium dihydrogen phosphate helps prevent rickets, osteomalacia, and weak bones in livestock.
2. Enhances Crop Yield and Soil Fertility
In agriculture, the compound is an essential phosphorus fertilizer. Phosphorus plays a crucial role in plant metabolism, aiding in processes like photosynthesis, energy transfer, and nutrient absorption. Calcium dihydrogen phosphate provides a slow-release form of phosphorus, ensuring a steady supply of this vital nutrient to plants over time.
● Sustained Nutrient Release: Unlike some phosphorus fertilizers that can be quickly leached from the soil, calcium dihydrogen phosphate helps improve nutrient retention in the soil, reducing the need for frequent reapplication.
● Soil pH Regulation: The calcium in the compound also helps in buffering soil pH, ensuring that the soil remains in a range that is conducive to plant growth. This helps prevent soil acidification and enhances soil structure.
3. Improves Bone and Dental Health in Humans
As a calcium source, calcium dihydrogen phosphate is beneficial for bone health in humans. It is often included in calcium supplements to prevent or treat osteoporosis, osteopenia, and calcium deficiency.
● Support for Bone Formation: The compound provides calcium, which is essential for the formation and maintenance of bones and teeth. It also plays a role in regulating muscle contractions and nerve transmission, making it crucial for overall musculoskeletal health.
4. Non-Toxic and Safe for Use
Calcium dihydrogen phosphate is generally considered non-toxic and safe for use in the various applications mentioned above. Its low environmental impact also makes it a preferred choice in agriculture and animal feed. It is less likely to cause the same environmental issues associated with other, more toxic chemical fertilizers.
● Sustainability: The compound is eco-friendly and can be safely used in organic farming, where the use of synthetic chemicals is restricted. As it is a natural source of calcium and phosphorus, it aligns with sustainability practices.
5. Improves Water Quality
In water treatment processes, calcium dihydrogen phosphate can help improve water quality by adjusting pH levels and removing certain impurities. This makes it valuable in industries that require precise water chemistry, including pharmaceutical manufacturing and food processing.

Calcium dihydrogenphoshate丨7758-23-8 is a highly versatile compound with applications across multiple industries, including agriculture, animal feed, pharmaceuticals, and industrial processes. Its main benefits lie in its ability to provide essential nutrients such as calcium and phosphorus, promoting growth, bone health, and productivity in animals and plants.

The compound's biological activity and non-toxic nature make it an attractive option for improving soil fertility, animal nutrition, and human health, as well as for use in various industrial applications. Given its broad spectrum of uses and benefits, calcium dihydrogen phosphate continues to be an important and widely utilized compound in several sectors.