2-Bromo-4'-chloro-1,1'-biphenyl丨CAS 179526-95-5

2-Bromo-4'-chloro-1,1'-biphenyl丨CAS 179526-95-5
Product Introduction:
Catalog No.: SS130324
CAS No.: 179526-95-5
Purity(HPLC): 99%min
Product Name: 2-Bromo-4'-chloro-1,1'-biphenyl
Molecular Formula: C12H8BrCl
Molecular Weight: 267.55
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Technical Parameters
Description

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Specifications

 

Appearance: White powder
Purity (HPLC): 99% min
Melting Point (MP): 39.0~42.0 °C

 

 

 

Applications

 

 

1. Organic Synthesis Intermediate

Used as a building block in the synthesis of more complex biphenyl-based molecules. The halogen substituents allow for selective functionalization via cross-coupling reactions (e.g., Suzuki, Heck, or Negishi couplings).

2. Pharmaceutical and Agrochemical Research

This compound serves as a precursor in the development of pharmaceuticals and agrochemicals. The biphenyl framework is commonly found in bioactive molecules, and the halogens facilitate the introduction of further functional groups.

3. Material Science

Applied in the synthesis of organic materials such as liquid crystals, polymers, and organic semiconductors. The biphenyl structure contributes to rigidity and planarity in molecular design.

4. Catalyst and Ligand Synthesis

Used to prepare ligands or catalysts featuring biphenyl moieties for homogeneous catalysis in various organic transformations.

Benefits

Selective Reactivity: The different halogen substituents enable site-specific reactions and functional group transformations.

Versatile Building Block: Provides structural rigidity and planarity, beneficial for designing molecules with specific electronic or steric properties.

Facilitates Complex Syntheses: Useful in multi-step syntheses where precise substitution patterns are necessary.

Stability: Halogenated biphenyls tend to be chemically stable, allowing for easy handling and storage.

Conclusion

2-Bromo-4'-chloro-1,1'-biphenyl is a crucial intermediate in organic synthesis, offering versatility in the creation of complex biphenyl derivatives. Its halogen substitutions provide reactive sites for further functionalization, making it valuable in pharmaceuticals, agrochemicals, and materials science. As a building block, it supports the development of advanced molecules with applications ranging from bioactive compounds to high-performance materials.

 

 

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