Methyl-d3-amine Monohydrochloride丨CAS 7436-22-8

Methyl-d3-amine Monohydrochloride丨CAS 7436-22-8
Product Introduction:
CAS No.: 7436-22-8
Product Name: Methyl-d3-amine monohydrochloride
Molecular Formula: CH6ClN
Molecular Weight: 70.54
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Technical Parameters
Description

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Methyl-d3-amine monohydrochloride, also known as deuterated methylamine hydrochloride, is an isotopically labeled amine salt in which the three hydrogen atoms of the methyl group are replaced by deuterium. This compound provides a source of deuterium-labeled methylamine for organic synthesis, pharmaceutical research, and isotope-labeling studies. Its primary amine functionality enables a range of chemical transformations, making it a useful building block for preparing labeled nitrogen-containing compounds.

 

Chemical Identifiers

 

InChI InChI=1S/CH5N.ClH/c1-2;/h2H2,1H3;1H/i1D3;
InChI Key NQMRYBIKMRVZLB-NIIDSAIPSA-N
Smiles [2H]C([2H])([2H])N.Cl
EC No.  
MDL No.  
PubChem CID 2723974

 

 

 

Applications

 

Isotope Effect and Mechanistic Studies

Replacing hydrogen with deuterium allows researchers to investigate kinetic isotope effects and reaction mechanisms. Methyl-d3-amine monohydrochloride offers a defined isotopic source for studying reactions involving methylamine-derived groups and evaluating how isotopic substitution influences chemical transformations.

Pharmaceutical Research and Drug Discovery

Deuterium-labeled building blocks are valuable in medicinal chemistry for preparing isotopically modified molecules and investigating their chemical and metabolic properties. Methyl-d3-amine monohydrochloride can serve as a starting material for introducing a deuterated methylamino group into pharmaceutical intermediates and research compounds, depending on the synthetic route.

Organic Synthesis and Labeled Building Blocks

The compound provides a convenient source of deuterated methylamine for suitable synthetic reactions. Its primary amine functionality can participate in reactions such as amination and other nitrogen-functionalization processes under appropriate conditions, supporting the preparation of deuterium-labeled amines, amides, and related compounds.

Analytical Chemistry and Mass Spectrometry Research

Deuterium-labeled compounds can support analytical method development and isotope-related investigations. Methyl-d3-amine monohydrochloride may be used to prepare labeled reference compounds or other analytical research materials when a deuterated methylamino unit is required. Its suitability depends on the target compound and analytical workflow.

 

 

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