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Specifications of L-Menthol丨CAS 2216-51-5
|
Property |
Specification |
|
Grade |
BP2005/USP32/GB1886.199-2016 |
|
Color and Appearance |
Colorless, transparent hexagonal or needlelike crystals |
|
Odor |
Characteristic odor of Chinese natural menthol |
|
Melting Point |
42–44°C |
|
Solubility (25°C) |
1 gram melts into 5 ml of 90% alcohol |
|
Non-volatile Content |
0.05% max |
|
Specific Rotation (20°C) |
-51 to -45° |
|
Arsenic Content |
2 mg/kg max |
|
Heavy Metal |
10 mg/kg max |
|
Purity |
99% min |
Overview
L-Menthol丨CAS 2216-51-5 is the naturally occurring isomer of menthol, primarily derived from peppermint and cornmint oils. It is widely used across multiple industries due to its cooling sensation, pleasant aroma, and therapeutic properties.
Applications of L-Menthol丨CAS 2216-51-5
1. Pharmaceuticals and Healthcare
√ Topical Analgesic
● L-Menthol丨CAS 2216-51-5 provides a cooling effect on the skin and mucous membranes by activating TRPM8 receptors (cold-sensing nerves).
● Used in ointments, gels, and sprays for relief of minor muscle and joint pain, itching, sprains, and headaches (e.g., menthol patches or roll-ons).
√ Decongestant and Cough Suppressant
● Found in throat lozenges, nasal inhalers, and cough drops to relieve nasal congestion, sore throat, and irritating cough.
√ Oral Hygiene
● Used in toothpastes, mouthwashes, and chewing gum for its refreshing flavor, antibacterial properties, and breath-freshening effect.
2. Food and Beverage Industry
√ Flavoring Agent
● Widely used to impart a cool, minty flavor in candies, chewing gum, desserts, chocolates, and beverages.
● Enhances the perception of freshness and can mask the bitterness of certain formulations.
√ Cooling Agent
● Offers a non-thermal cooling sensation, often used in energy drinks, mints, and confectionery.
3. Cosmetics and Personal Care
√ Fragrance and Sensory Enhancer
● Added to shampoos, shower gels, soaps, and lotions for its fresh scent and cooling effect on skin and scalp.
● Enhances user experience by providing a tingling, refreshing sensation.
√ Aftershaves and Balms
● Soothes skin after shaving and reduces irritation.
4. Tobacco and Vaping Products
● Used in menthol cigarettes and e-cigarette liquids to provide a cooling mouthfeel and mask harshness of smoke or vapor.
Note: Regulatory limitations apply in many countries due to health and marketing concerns.
5. Industrial and Veterinary Applications
● Used in animal care products (e.g., sprays and rubs for horses or livestock).
● Sometimes added to cooling balms or tick repellents.
Benefits of L-Menthol丨CAS 2216-51-5
√ Powerful Cooling Effect
● Activates cold-sensitive receptors without actual temperature change.
● Offers relief in pain, itching, and irritation.
√ Antimicrobial and Antifungal Activity
● Provides natural protection against certain bacteria and fungi, especially in oral and personal care products.
√ Natural and Recognized Safe
● Considered GRAS (Generally Recognized as Safe) by the FDA for use in foods.
● Naturally derived and biodegradable.
√ Multisensory Enhancement
● Enhances taste, smell, and skin feel, making it highly valuable in consumer products.
Conclusion
L-Menthol丨CAS 2216-51-5 is a versatile and multifunctional compound prized for its natural origin, refreshing properties, and therapeutic benefits. Whether used in medicine, cosmetics, food, or flavors, it remains one of the most popular bioactive terpenoids in the global market.
