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Specifications of Benzaldehyde dimethyl acetal丨CAS 1125-88-8
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Appearance |
Colorless clear liquid |
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Purity |
99% min (Calculate according to the normalization method) |
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Max single impurity |
0.5% max |
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Identification |
The retention time is consistent with the spectrum of the reference substance |
Transport Information of Benzaldehyde dimethyl acetal丨CAS 1125-88-8
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Parameter |
Specification |
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UN Number |
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Class |
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Packing Group |
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H.S. Code |
2911000000302 |
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Stability & Reactivity |
Forms explosive mixtures with air on intense heating. |
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Storage |
Tightly closed. Moisture sensitive. |
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Condition to Avoid |
Moisture |
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Package |
Manufacturing Information of Benzaldehyde dimethyl acetal丨CAS 1125-88-8
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Parameter |
Specification |
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Capacity |
5MT/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2010 |
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Stock |
Overview
Benzaldehyde dimethyl acetal丨CAS 1125-88-8 is the dimethyl acetal derivative of benzaldehyde, often used as a protected form of benzaldehyde in organic synthesis. It is stable under neutral or basic conditions and can be hydrolyzed back to benzaldehyde under acidic conditions.
Applications
1. Organic Synthesis Intermediate
Acts as a protected aldehyde in multi-step organic syntheses to prevent unwanted side reactions at the aldehyde group.
Used in:
Grignard reactions
Aldol condensations
Reductive amination or hydrogenation steps
2. Fragrance and Flavor Industry
Imparts a mild floral, fruity aroma; used in:
Perfumes and fragrances as a fixative or blender
Flavors for food and beverages in trace amounts (must meet food-grade specifications)
3. Pharmaceutical and Fine Chemical Manufacturing
Serves as an intermediate or protecting group in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals.
Useful for constructing aromatic or benzylic moieties in drug candidates.
4. Research and Development
Employed in academic and industrial R&D for reaction mechanism studies involving acetals or protected aldehydes.
Used to investigate acid-catalyzed hydrolysis, stability, and protective strategies in lab settings.
Benefits
1. Aldehyde Protection
Converts reactive benzaldehyde into a more stable acetal, allowing selective functional group transformations without interfering with the aldehyde.
Easily hydrolyzed under mild acidic conditions to regenerate benzaldehyde.
2. Chemical Stability
Stable to bases and neutral conditions; not prone to oxidation or condensation like free aldehydes.
Enhances shelf life and handling safety in sensitive reactions.
3. Versatile Reactivity
Compatible with a broad range of reagents and solvents.
Useful in both batch and continuous-flow synthesis systems.
4. Mild Aroma and Low Toxicity (in Limited Use)
Compared to benzaldehyde, it has a less pungent odor and is more manageable in enclosed lab environments.
However, industrial use must still follow proper ventilation and PPE protocols.
Conclusion
Benzaldehyde dimethyl acetal丨CAS 1125-88-8 is a useful protective intermediate in organic and pharmaceutical chemistry. Its ability to temporarily mask the reactivity of benzaldehyde makes it valuable in multi-step syntheses. Additionally, its fragrance applications and compatibility with a wide range of reagents make it attractive in both industrial and research settings. With proper handling, it offers stability, versatility, and synthetic utility across multiple sectors.
