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Specifications
| Grade: | FCC V |
| Appearance: | White to off-white crystalline powder |
| Assay (GC): | 99.0% min |
| Odor: | Rich odor of coconut |
| Identification: | IR spectrum matches the reference standard |
| Solubility: | 1 g soluble in 20 mL 95% Alcohol at 25°C |
| Heavy Metal: | 10 ppm max |
| Melting Point: | 73–76°C |
Applications
6-Methyl-2H-chromen-2-one (CAS 92-48-8) is a coumarin derivative widely used in pharmaceutical, fragrance, and chemical research. In medicinal chemistry, it serves as an intermediate for the synthesis of anticoagulants, anti-inflammatory agents, and other bioactive molecules. Its coumarin scaffold is also applied in the design of fluorescent probes, enzyme inhibitors, and photoreactive compounds. Additionally, 6-methyl-2H-chromen-2-one is utilized in the fragrance industry to impart sweet, hay-like, and vanilla-like notes in perfumes and cosmetic formulations, and as a building block for dyes and organic materials with photophysical properties.
Benefits
The benefits of 6-methyl-2H-chromen-2-one derive from its stable coumarin ring and reactive functional groups. The methyl substitution at position 6 enhances lipophilicity and electronic properties, facilitating selective chemical transformations such as alkylation, acylation, and cyclization. Its aromatic lactone structure provides stability, fluorescence, and compatibility with a variety of synthetic reactions. These features allow efficient synthesis of bioactive molecules, fluorescent probes, and fragrance compounds, making it a versatile intermediate in both research and industrial applications.
Conclusion
6-Methyl-2H-chromen-2-one is a versatile coumarin derivative with applications in pharmaceuticals, fragrances, and chemical research. Its stable aromatic lactone core, reactive sites, and methyl substitution enable the synthesis of bioactive compounds, fluorescent probes, and aromatic materials. By supporting chemical innovation and product development, it remains an important intermediate in both industrial and research settings.
