Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of l(+)-ergothioneine丨cas 497-30-3 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications of L(+)-Ergothioneine丨CAS 497-30-3
|
Appearance |
White to off white powder |
|
Purity (HPLC) |
99% min |
|
Loss on Drying |
0.5% max |
|
Total Residual Solvents |
500 ppm max |
|
Heavy Metal Content |
Pb: 0.5 ppm max |
|
Total Microbial Count |
1000 cfu/g max |
|
Coliform |
0.92 MPN/g max |
|
Mold and Yeast |
100 cfu/g max |
|
Staphylococcus aureus |
0/25g |
|
Salmonella |
0/25g |
Transport Information of L(+)-Ergothioneine丨CAS 497-30-3
|
Parameter |
Specification |
|
UN Number |
|
|
Class |
|
|
Packing Group |
|
|
H.S. Code |
2933990099306 |
|
Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
|
Storage |
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Storage stability Recommended storage temperature -20 °C |
|
Condition to Avoid |
Avoid moisture. |
|
Package |
Manufacturing Information of L(+)-Ergothioneine丨CAS 497-30-3
|
Parameter |
Specification |
|
Capacity |
500kg/month |
|
Frequency |
|
|
Main Export Countries |
US, Japan |
|
Capacity/Batch |
|
|
Experience |
Production since 2019 |
|
Stock |
Applications
1. Pharmaceuticals and Nutraceuticals
L(+)-Ergothioneine丨CAS 497-30-3 is gaining attention for its antioxidant and cytoprotective properties:
Antioxidant therapy: Neutralizes reactive oxygen species (ROS) and protects against oxidative stress
Anti-inflammatory agent: May reduce chronic inflammation through indirect NF-κB pathway modulation
Neuroprotective potential: Investigated for delaying the onset or progression of neurodegenerative diseases such as Alzheimer's and Parkinson's
Cardiovascular support: Shown in preliminary studies to reduce oxidative damage in heart and vascular tissues
Liver and kidney protection: Helps preserve organ function under stress from drugs, alcohol, or toxins
2. Cosmetic and Personal Care
Used as an active ingredient in anti-aging formulations due to its ability to combat oxidative stress at the cellular level
Protects skin from UV-induced damage, pollution, and blue light
Supports collagen preservation and skin brightening
3. Food and Beverage Industry
Promoted as a novel antioxidant dietary supplement in functional foods and beverages
Often incorporated into mushroom-based superfoods, health drinks, or antioxidant capsules
4. Biomedical Research
Utilized as a tool in cell biology and oxidative stress studies
Acts as a bioindicator for transport mechanisms due to its selective uptake via the OCTN1 transporter (SLC22A4)
Key Benefits
✅ Potent Antioxidant
Ergothioneine scavenges a broad spectrum of reactive species: hydroxyl radicals, singlet oxygen, hypochlorite, and peroxynitrite
More stable and less toxic than glutathione in certain biological contexts
Unlike other antioxidants, it does not undergo auto-oxidation
✅ Cellular Protection
Accumulates in mitochondria and nucleus, safeguarding DNA and energy-producing systems
Reduces cellular apoptosis under stress or toxic environments
✅ Selective Uptake and Long Half-Life
Actively transported into cells by OCTN1, which shows high tissue specificity
Long intracellular half-life means prolonged protection even with low dietary intake
✅ Anti-Aging and Neuroprotection
Preliminary animal studies and epidemiological data suggest potential benefits in reducing age-related cognitive decline and enhancing cellular longevity
✅ Safe and Well-Tolerated
No significant adverse effects reported in clinical or dietary exposures
Deemed safe by EFSA (European Food Safety Authority) and FDA (U.S.) for use in supplements and food
Conclusion
L(+)-Ergothioneine丨CAS 497-30-3 is a unique naturally occurring antioxidant with powerful cytoprotective, anti-inflammatory, and anti-aging properties. Its selective uptake and long cellular retention make it highly efficient for protecting sensitive tissues from oxidative stress and environmental damage. As interest grows in natural, functional bioactives, ergothioneine continues to attract attention in the fields of pharmaceuticals, nutraceuticals, and cosmetics.
