Urolithin B丨CAS 1139-83-9

Urolithin B is a naturally derived phenolic compound belonging to the urolithin family, formed through the intestinal microbial metabolism of ellagitannins and ellagic acid found in pomegranates, berries, and nuts. It has attracted significant attention in the pharmaceutical, nutraceutical, and cosmetic industries due to its potent biological activities. In pharmaceuticals, Urolithin B is being studied for its antioxidant, anti-inflammatory, anti-cancer, and neuroprotective properties, showing potential in treating metabolic and degenerative diseases. In nutraceuticals, it serves as an active ingredient in dietary supplements formulated to enhance muscle performance, promote mitochondrial health, and support healthy aging. In cosmetics, Urolithin B is used in skin care formulations for its anti-aging and protective effects against oxidative stress and UV-induced damage. Furthermore, it has applications in biomedical research as a biomarker and model compound for studying gut microbiome–derived metabolites and their physiological impacts.

Urolithin B provides a wide range of biological and functional benefits owing to its strong antioxidant and anti-inflammatory mechanisms. It helps scavenge free radicals, reduce oxidative damage, and modulate key signaling pathways involved in inflammation and cellular stress. Studies have shown that Urolithin B promotes muscle protein synthesis and may counteract muscle atrophy, making it valuable for sports nutrition and geriatric health. Its neuroprotective and cardioprotective effects are linked to improved mitochondrial function and enhanced cellular resilience, contributing to longevity and disease prevention. In topical and oral formulations, Urolithin B demonstrates good bioavailability and stability, making it suitable for both preventive and therapeutic applications. Its natural origin and safety profile further enhance its appeal as a functional ingredient in health and wellness products.