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Specifications of Sodium 1-octanesulfonate丨CAS 5324-84-5
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Appearance: |
White solid |
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Content: |
99.5% – 100.5% |
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Solubility: |
(10% in water) clear, colorless |
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UV (0.05 M aq. soln.) (1 cm cell vs HPLC water): |
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at 200 nm A: |
0.100 max |
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at 210 nm A: |
0.050 max |
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at 220 nm A: |
0.030 max |
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at 230 nm A: |
0.100 max |
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at 240 nm A: |
0.100 max |
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at 250 nm A: |
0.100 max |
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at 260 nm A: |
0.100 max |
Transport Information of Sodium 1-octanesulfonate丨CAS 5324-84-5
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Parameter |
Specification |
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UN Number |
3261 |
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Class |
8 |
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Packing Group |
II |
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H.S. Code |
2904100000302 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions (room temperature). |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place |
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Condition to Avoid |
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Package |
Manufacturing Information of Sodium 1-octanesulfonate丨CAS 5324-84-5
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Parameter |
Specification |
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Capacity |
1MT/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2005 |
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Stock |
Sodium 1-octanesulfonate丨CAS 5324-84-5, also known as sodium octane-1-sulfonate, is the sodium salt of an aliphatic sulfonic acid. It is widely used in analytical chemistry, pharmaceutical research, and chromatographic separations, primarily due to its surface-active and ion-pairing properties.
Key Applications of Sodium 1-octanesulfonate丨CAS 5324-84-5
1. Ion-Pair Reagent in HPLC
Sodium 1-octanesulfonate丨CAS 5324-84-5 is widely used in reversed-phase high-performance liquid chromatography (RP-HPLC) as an ion-pairing agent. It improves the retention and separation of polar or ionic compounds, particularly:
● Basic drugs
● Amines
● Peptides
● Alkaloids
Its use enhances the resolution of analytes that otherwise elute poorly or not at all on conventional C18 columns.
2. Pharmaceutical Analysis
In pharmaceutical laboratories, sodium 1-octanesulfonate is used for the quantitative and qualitative analysis of active pharmaceutical ingredients (APIs), including antibiotics and antihistamines, by forming ion pairs that enhance UV absorbance and improve chromatographic behavior.
3. Surface-Active Agent
It acts as a surfactant and wetting agent in various analytical and industrial applications, contributing to solubilization and stabilization of hydrophobic compounds in aqueous media.
4. Analytical Reagent
Used in research and development settings for method validation, especially in bioanalytical studies, including plasma drug level determinations.
Benefits of Sodium 1-octanesulfonate丨CAS 5324-84-5
✅ Enhanced Chromatographic Performance
Improves peak shape, resolution, and retention for polar analytes that are difficult to separate using standard methods.
✅ High Solubility and Compatibility
Easily dissolves in aqueous mobile phases and compatible with a wide range of buffers and organic modifiers like methanol and acetonitrile.
✅ Reliable and Reproducible
Ensures consistent results across analytical runs, crucial for validated pharmaceutical methods and regulated environments.
✅ Broad Utility in Research
Useful in method development and compound profiling across pharmaceuticals, biotechnology, and environmental science.
