Hangzhou Leap Chem Co., Ltd. is one of the most professional manufacturers and suppliers of wang resin丨cas 201058-08-4 in China. Welcome to wholesale bulk high quality chemical products at competitive price from our factory. If you have any enquiry about custom service, please feel free to email us.
Specifications
| Appearance: | Slight yellow or yellow beads |
| Bead Size: | 100 to 200 mesh |
| Substitution: | 1-1.2 mmol/g |
| Loss on drying (105°C): | 2.0% max |
| Degree of Swelling in DCM for 4 hours: | 4 to 10 ml/g |
| Degree of Swelling in DMF for 4 hours: | 4 to 8 ml/g |
| Kaiser Test (100°C, 3-5 min): | Negative |
| IR: | Compared with standard IR spectrum |
Transport Information
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H.S. Code |
3906909090302 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Store in a closed, dry, ventilated place |
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Condition to Avoid |
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Package |
Manufacturing Information
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Specification |
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Capacity |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2018 |
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Stock |
2MT |
Applications
1. Solid-Phase Peptide Synthesis (SPPS)
Wang resin is widely used as a solid support for peptide synthesis.
Enables stepwise assembly of peptides by anchoring the C-terminal amino acid.
After peptide chain assembly, peptides can be cleaved from the resin under acidic conditions (typically trifluoroacetic acid, TFA).
2. Combinatorial Chemistry
Used in creating peptide libraries for drug discovery and biochemical research.
3. Bioconjugation and Molecular Biology
Facilitates synthesis of peptides with specific sequences for enzyme substrates, inhibitors, or probes.
Benefits
High Loading Capacity: Efficient attachment of amino acids for peptide elongation.
Acid-Labile Linker: Allows peptide cleavage without harsh conditions, preserving peptide integrity.
Mechanical Stability: Durable resin beads support repeated synthesis cycles.
Compatibility: Suitable for Fmoc and Boc peptide synthesis strategies.
Facilitates Purification: Solid-phase method simplifies washing and purification steps during synthesis.
Conclusion
Wang resin (CAS 201058-08-4) is a key solid-phase support in peptide synthesis, allowing efficient assembly and mild cleavage of peptides. Its acid-labile linker and robust physical properties make it indispensable in biochemical research, drug discovery, and peptide production.
