Nitrilotriacetic Acid丨CAS 139-13-9

1. Physical Properties:

- Appearance: White crystalline powder.

- Melting Point: 242 °C (decomposes).

- Solubility: Soluble in water and alkaline solutions; slightly soluble in organic solvents.

- pKa Values: NTA has three carboxyl groups with pKa values of approximately 1.9, 2.5, and 9.7.

2. Chemical Properties:

- Nitrilotriacetic acid丨139-13-9 is a chelating agent, capable of forming stable complexes with metal ions such as calcium, magnesium, iron, and copper.

- It is biodegradable under certain conditions, making it an environmentally friendly alternative to other chelating agents like EDTA.

1. Detergents and Cleaning Agents:

- NTA is used as a water softener in detergents and cleaning products. It binds to metal ions in hard water, preventing them from interfering with the cleaning process.

- It is particularly effective in removing scale and stains caused by metal ions.

2. Industrial Water Treatment:

- Nitrilotriacetic acid丨139-13-9 is used to control scale formation and corrosion in boilers, cooling towers, and other industrial water systems.

- It helps maintain the efficiency of heat exchangers and other equipment by preventing metal ion deposits.

3. Agriculture:

- NTA is used in fertilizers and micronutrient formulations to improve the availability of essential metal ions (e.g., iron, zinc) to plants.

- It is also used in hydroponic systems to deliver nutrients to plants in a soluble form.

4. Pharmaceuticals and Cosmetics:

- NTA is used as a stabilizer and chelating agent in pharmaceutical formulations and cosmetic products.

- It helps maintain the stability and efficacy of active ingredients by sequestering metal ions that could catalyze degradation.

5. Analytical Chemistry:

- Nitrilotriacetic acid丨139-13-9 is used as a complexing agent in titrations and other analytical methods to determine metal ion concentrations.

- It is also used in buffer solutions to control pH and metal ion activity.

6. Pulp and Paper Industry:

- NTA is used to improve the brightness and quality of paper by chelating metal ions that can cause discoloration.

7. Textile Industry:

- NTA is used in dyeing processes to improve color fastness and prevent metal ion interference.

1. Effective Chelation:

- NTA forms stable complexes with a wide range of metal ions, making it highly effective in applications requiring metal ion control.

2. Biodegradability:

- Unlike some other chelating agents, NTA is biodegradable under aerobic conditions, reducing its environmental impact.

3. Versatility:

- Nitrilotriacetic acid丨139-13-9 is used in a wide range of industries, from detergents and agriculture to pharmaceuticals and water treatment.

4. Cost-Effectiveness:

- NTA is relatively inexpensive and readily available, making it a cost-effective choice for many applications.

1. Toxicity:

- NTA is generally considered to have low acute toxicity. However, prolonged exposure to high concentrations may cause irritation to the skin, eyes, and respiratory tract.

- It is not classified as a carcinogen, but some studies suggest potential reproductive and developmental toxicity at high doses.

2. Environmental Impact:

- Nitrilotriacetic acid丨139-13-9 is biodegradable, but its breakdown products can persist in the environment and may contribute to the mobilization of heavy metals in soil and water.

- It should be used and disposed of in accordance with local regulations to minimize environmental impact.

3. Handling Precautions:

- Use personal protective equipment (PPE), including gloves, goggles, and lab coats, when handling NTA.

- Avoid inhalation of dust and contact with skin and eyes.

- Store in a cool, dry place away from incompatible substances such as strong oxidizing agents.

4. Regulatory Status:

- NTA is approved for use in detergents and other applications in many countries, but its use is regulated due to potential environmental concerns.

Nitrilotriacetic acid丨139-13-9 is a versatile and effective chelating agent with applications in detergents, water treatment, agriculture, pharmaceuticals, and more. Its ability to form stable complexes with metal ions makes it invaluable in controlling scale, improving nutrient availability, and stabilizing formulations. While NTA is biodegradable and generally considered safe, proper handling and disposal are essential to minimize potential health and environmental risks. Its cost-effectiveness and versatility ensure its continued use across a wide range of industries.