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Specifications
| Description: | White crystal |
| Purity: | 98%min |
| Melting point: | 58-65 deg C |
| Insoluble: | 0.05% max |
| Incandescent residue: | 0.05% max |
Transport Information
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Parameter |
Specification |
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UN Number |
2811 |
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Class |
6 |
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Packing Group |
III |
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H.S. Code |
2928000090309 |
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Stability & Reactivity |
The product is chemically stable under standard ambient conditions. |
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Storage |
Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons. |
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Condition to Avoid |
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Package |
Manufacturing Information
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Parameter |
Specification |
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Capacity |
10MT/month |
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Frequency |
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Main Export Countries |
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Capacity/Batch |
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Experience |
Production since 2005 |
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Stock |
Applications
1. Intermediate in Pharmaceutical Synthesis
Serves as a key building block in the synthesis of:
Hydrazones, pyrazoles, and triazoles
Antitubercular agents, such as isoniazid analogs
Antibacterial, antiviral, antitumor, and antifungal compounds
Used in research and development of central nervous system (CNS) drugs
2. Agricultural Chemicals
Functions as an intermediate in the production of pesticides, herbicides, and fungicides.
Useful in modifying bioactivity profiles of agrochemicals to improve efficacy and stability.
3. Organic Synthesis
Acts as a nucleophile in reactions forming:
Heterocyclic rings
Schiff bases
Hydrazone linkages
Involved in creating complex ligands for metal coordination chemistry
4. Polymer and Material Science
Used in modification of polymers and resins, especially those requiring nitrogen-containing functional groups.
Studied for potential applications in energetic materials and fuel additives due to its nitrogen content.
5. Analytical Chemistry
Employed in derivatization for spectrophotometric or chromatographic detection of carbonyl compounds.
May also serve in detection kits for trace aldehyde/ketone analysis via hydrazone formation.
Benefits
🧬 Versatile Reactivity
The hydrazide group makes it highly reactive toward:
Aldehydes and ketones (forming hydrazones)
Acids and acylating agents
This enables its wide use across medicinal, agrochemical, and industrial research.
💊 Small Molecule Precursor
Its low molecular weight and simple structure make it a useful starting material or scaffold for designing complex drug molecules or ligand systems.
🌱 Eco-Friendly Synthetic Pathways
Acethydrazide can be incorporated into greener synthesis protocols owing to its low toxicity and biodegradability under certain conditions.
🧫 Broad Research Utility
Supports the development of biologically active compounds through simple structure modification, increasing the diversity of lead molecules in drug discovery.
Conclusion
Acethydrazide (CAS 1068-57-1) is a highly useful chemical intermediate recognized for its role in organic synthesis, pharmaceutical development, and agrochemical production. Its versatile reactivity, particularly the ability to form hydrazones and heterocycles, makes it essential for crafting complex molecular structures. With broad applicability across both scientific research and industrial chemistry, acethydrazide remains a key compound in the advancement of chemical innovation, especially in the fields of drug discovery and materials science.
