Hello, Welcome to LEAPChem.com

Order Dibenzoylmethane (120-46-7) from LEAPChem Now!

Nov. 2018/7/5 16:10:44 By LEAP Chem


Searching for niche products has always been a problem. You have to spend much valuable time looking for a supplier, and then you need to make sure the provider is reputable. Usually, successfully finding a reputable, reliable, and responsible supplier of high quality chemicals must be a headache. Relax now, because those days are over! By coming to the LEAPChem - Pharmaceutical Chemicals website, you have come one step closer to acquiring your trouble free pharmaceutical chemicals. LEAPChem Highlights Dibenzoylmethane today!

 

Basic Information of Dibenzoylmethane

Chemical Name: Dibenzoylmethane

Cas No.: 120-46-7

Molecular Formula: C15H12O2

Chemical Structure:

 120-46-7.png

 

1,3-Diphenyl-1,3-propanedione (dibenzoylmethane, DBM) is an aromatic 1,3-diketone derivative of acetylacetone (acac), where both methyl groups in acac have been substituted by phenyl groups. It is a white solid melting at 77?78 °C. Similar to acac, DBM exists in two tautomeric forms, with the keto-enol equilibrium of DBM shifting strongly towards the enol form, particularly in non-polar solvents such as benzene. This is the result of the stability of the intramolecular hydrogen bond in the cis-enol form which is further resonance-stabilized by conjugation with phenyl rings. Due to its high photostability, derivatives of DBM such as avobenzone, have found applications as sunscreen products.

Dibenzoylmethane (DBM) is a natural phytochemical found as a minor constitute in the root extract of Licorice (Glycyrrhiza glabra in the family Leguminosae), and it is a beta-diketone phytochemical with a wide variety of anti-cancer effects. DBM has been shown to prevent the formation of DNA-adducts induced by carcinogen in both in vitro and in vivo studies. DBM could induce apoptosis in human prostate and colon cancer cells, and induce cycle arrest in prostate cancer cells. An investigational use in the treatment of neurodegenerative diseases has been suggested; in the study DBM (and Trazodone) demonstrated potential in slowing disease progression, by preventing the cessation of protein synthesis in neurons.

 

Allow a company with a ISO 9001 certification to handle all your pharmaceutical chemical needs. From finding a reliable manufacturer who creates a quality product meeting your specifications, to shipping to the port or facility to your choice, LEAPChem’s experienced and professional staff will make the process as smooth as possible.
If you are interested in Dibenzoylmethane, click here to send an inquiry!

Make LEAPChem your pharmaceutical chemicals long-term partner and contact us today!

 

References:

https://en.wikipedia.org/wiki/Dibenzoylmethane

https://www.ncbi.nlm.nih.gov/pubmed/12646199

https://www.ncbi.nlm.nih.gov/pubmed/25756788

 

Related Articles

Order Estradiol (50-28-2) from LEAPChem Now!

LEAPChem Supplies Menadione (58-27-5) Now!

Source Sildenafil citrate (171599-83-0) from LEAPChem Now!